Results 51 to 60 of about 1,178,243 (306)

Pathophysiology, Management, and Therapeutics in Subarachnoid Hemorrhage and Delayed Cerebral Ischemia: An Overview

Pathophysiology, 2023
Subarachnoid hemorrhage (SAH) is a type of hemorrhagic stroke resulting from the rupture of an arterial vessel within the brain. Unlike other stroke types, SAH affects both young adults (mid-40s) and the geriatric population.
Henry W. Sanicola, Caleb E. Stewart, Patrick Luther, Kevin Yabut, Bharat Guthikonda, J. Dedrick Jordan, J. Steven Alexander   +6 more
doaj   +1 more source

Diabetic Ketoacidosis: Pathophysiology and Treatment [PDF]

, 2015
The pathophysiology of DKA in patients with T1D is addressed, followed by a discussion of proper emergency treatment for this life-threatening ...
Mumme, Laura E.
core   +1 more source

Wearable sensors system for an improved analysis of freezing of gait in Parkinson's disease using electromyography and inertial signals [PDF]

, 2019
We propose a wearable sensor system for automatic, continuous and ubiquitous analysis of Freezing of Gait (FOG), in patients affected by Parkinson's disease.
Gumiero, Alessandro, Irrera, Fernanda, Mazzetta, Ivan, Pessione, Marco, Suppa, Antonio, Zampogna, Alessandro   +5 more
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Shift of N-MYC Oncogene Expression in AML Patients Carrying the FLT3-ITD Mutation

Pathophysiology, 2023
Mutations in the FLT3 gene not only lead to abnormalities in its structure and function, but also affect the expression of other genes involved in leukemogenesis.
Konstantin Bogdanov, Ekaterina Kudryavtseva, Yulia Fomicheva, Irina Churkina, Elza Lomaia, Larisa Girshova, Yuri Osipov, Andrey Zaritskey   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Polymicrobial Infection (Gram-Positive and Gram-Negative) Exacerbates Systemic Inflammatory Response Syndrome in a Conscious Swine Extremity Trauma Model

Pathophysiology
Background/Objectives: Extremity trauma represents a significant proportion of battlefield injuries and is prevalent in polytraumatized patients from accidents.
Catharina C. Gaeth, Travis R. Madaris, Jamila M. Duarte, Amber M. Powers, Christina M. Sandoval, Stefanie M. Shiels, Randolph Stone   +6 more
doaj   +1 more source

Shock-Associated Systemic Inflammation in Amniotic Fluid Embolism, Complicated by Clinical Death

Pathophysiology, 2023
Background: Amniotic fluid embolism (AFE) is one of the main causes of maternal mortality in developed countries. The most critical AFE variants may be considered from the perspective of systemic inflammation (SI), a general pathological process that ...
Anatoly Brazhnikov, Natalya Zotova, Liliya Solomatina, Alexey Sarapultsev, Alexey Spirin, Evgeni Gusev   +5 more
doaj   +1 more source

Pathophysiology of Asthma [PDF]

British Journal of Clinical Pharmacology, 1996
1Our understanding of asthma and its therapy has changed markedly over the last few years, particularly with the application of molecular and cell biology and the discovery of new and more specific pharmacological tools. 2Many inflammatory cells participate in the inflammatory process in asthma and mediate a complex mixture of mediators. Cytokines are
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source