Results 51 to 60 of about 850,363 (310)
Isometric Handgrip Exercise Training Improves Spirometric Parameters and Pulmonary Capacity
Pathophysiology, 2021 Decline in normal physiological pulmonary function has been attributed to premorbid conditions such as prehypertension. Research evidence suggests that physical activity reduces age-related decline in pulmonary function and improves the efficiency of the
Ogbutor Udoji Godsday +6 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Pathophysiology, 2021 Acidosis and its associated pathologies predispose patients to develop cardiac arrhythmias and even cardiac arrest. These arrhythmias are assumed to be the result of membrane depolarization, however, the exact mechanism of depolarization during acidosis ...
Omar Ababneh +10 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Circulating Levels of Endothelin-1 and Big Endothelin-1 in Patients with Essential Hypertension
Pathophysiology, 2021 The role of endothelin-1 (ET-1) in the pathogenesis of hypertension (HTN) is not clearly established. There is evidence that its circulating levels are elevated in some forms of experimental and human HTN, but this was not a consistent finding.
Krasimir Kostov, Alexander Blazhev
doaj +1 more source
New Experimental Models In The Research Of The Pathophysiology Of The Cardiovascular System [PDF]
, 2021 The constant advances in the field of pathophysiology, nuclear medicine, and the treatment of cardiovascular diseases have set new demands for the experimental models used to simulate the diseases in the human body.The aim of this review is to highlight ...
Bratoeva, Kameliya; Department of Physiology and Pathophysiology, Medical University of Varna +3 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells
Pathophysiology, 2021 Cannabinoids are abundant signaling compounds; their influence predominantly arises via engagement with the principal two G-protein-coupled cannabinoid receptors, CB1 and CB2.
Mansour Haddad
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Description and Implementation: Cardiac Pathophysiology
Implementation guide for cardiac pathophysiology educational resources that correlate bedside cardiac assessment findings with underlying disease mechanisms.
core +1 more source