Results 51 to 60 of about 1,115,813 (356)
The Endothelial Glycocalyx and Retinal Hemodynamics
Pathophysiology, 2022 Purpose. Previous studies suggest that the endothelial glycocalyx adds to vascular resistance, inhibits thrombosis, and is critical for regulating homogeneous blood flow and ensuring uniform red blood cell (RBC) distribution. However, these functions and
Gaganpreet Kaur +2 more
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Pathophysiology, 2022 Transforming growth factor beta (TGFβ) is a versatile cytokine. Although a profibrotic role of TGFβ is well established, its effect on tissue inhibitor of metalloproteinase (TIMPs) and inflammatory mediators are incompletely described.
Babu Raja Maharjan +3 more
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Obesity: Epidemiology, Pathophysiology, and Therapeutics
Frontiers in Endocrinology, 2021 Obesity is a complex multifactorial disease that accumulated excess body fat leads to negative effects on health. Obesity continues to accelerate resulting in an unprecedented epidemic that shows no significant signs of slowing down any time soon. Raised
Xihua Lin, Hong Li
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Anatomical Theories of the Pathophysiology of Cancer-Related Lymphoedema
, 2020 Lymphoedema is a well-known concern for cancer survivors. A crucial issue in lymphoedema is that we cannot predict who will be affected, and onset can occur many years after initial cancer treatment.
Hiroo Suami
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Epidemiology and pathophysiology of cancer-associated thrombosis [PDF]
, 2010 Venous thromboembolism (VTE) is a common complication in patients with malignant disease. First recognised by Bouillard in 1823 and later described by Trousseau in 1844, multiple studies have since provided considerable evidence for a clinical ...
Pasi, J +5 more
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The Role of AP-1 Transcription Factors in Plasma Cell Biology and Multiple Myeloma Pathophysiology
, 2021 Multiple myeloma (MM) is an incurable hematologic malignancy characterized by the clonal expansion of malignant plasma cells within the bone marrow. Activator Protein-1 (AP-1) transcription factors (TFs), comprised of the JUN, FOS, ATF and MAF multigene ...
Klaus Podar, Fengjuan Fan
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Pathophysiology: Altered Physiological States
, 2018 Pathophysiology is the convergence of pathology (the discipline of observed changes in a diseased state) with physiology (the mechanisms of systems operation). It represents the functional changes that occur because of injury or disease.
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PathophysiologyThe vagina is an essential component of the female reproductive system and is responsible for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial role in various physiological processes, including sexual arousal ...
Chitaranjan Mahapatra, Ravinder Kumar
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Sepsis—Pathophysiology and Therapeutic Concepts
Frontiers in Medicine, 2021 Sepsis is a life-threatening condition and a global disease burden. Today, the heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated host response to infection, with renewed emphasis on immune pathophysiology. Despite all
D. Jarczak, S. Kluge, A. Nierhaus
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Histologic Analysis of ‘Distraction Vaginogenesis’ in a Rat Model
PathophysiologyVaginal agenesis (VA) is frequently associated with mullerian agenesis. VA treatments include mechanical dilation and surgical vaginoplasty. We created a vaginal expansion sleeve (VES) as a novel device to progressively lengthen the vaginal canal.
Hannah Meyer +11 more
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