Results 31 to 40 of about 940,129 (290)
Obesity: Epidemiology, Pathophysiology, and Therapeutics
Frontiers in Endocrinology, 2021 Obesity is a complex multifactorial disease that accumulated excess body fat leads to negative effects on health. Obesity continues to accelerate resulting in an unprecedented epidemic that shows no significant signs of slowing down any time soon. Raised
Xihua Lin, Hong Li
semanticscholar +1 more source
Pathophysiology, 2022 In pulmonary hypertension (PH), the development of right ventricular (RV) dilatation and RV failure are signs of accelerated progression of the disease, resulting in an increased risk of cardiac death.
Walter Serra, Alfredo Chetta
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Pathophysiology, 2022 A spontaneous coronary artery dissection (SCAD) during the postpartum period is a serious medical emergency and the most important non-atherosclerotic cause of coronary artery disease (CAD) in this population. While conservative management is recommended
Jaksa Zanchi +7 more
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The Endothelial Glycocalyx and Retinal Hemodynamics
Pathophysiology, 2022 Purpose. Previous studies suggest that the endothelial glycocalyx adds to vascular resistance, inhibits thrombosis, and is critical for regulating homogeneous blood flow and ensuring uniform red blood cell (RBC) distribution. However, these functions and
Gaganpreet Kaur +2 more
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Pathophysiology of Atherosclerosis
International Journal of Molecular Sciences, 2022 Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and, followed by a cascade of events (accumulation of lipids, fibrous ...
S. Jebari-Benslaiman +7 more
semanticscholar +1 more source
Pathophysiology, 2022 Transforming growth factor beta (TGFβ) is a versatile cytokine. Although a profibrotic role of TGFβ is well established, its effect on tissue inhibitor of metalloproteinase (TIMPs) and inflammatory mediators are incompletely described.
Babu Raja Maharjan +3 more
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Role of Candida albicans in Oral Carcinogenesis
Pathophysiology, 2022 Oral carcinogenesis is also dependent on the balance of the oral microbiota. Candida albicans is a member oral microbiota that acts as an opportunistic pathogen along with changes in the epithelium that can predispose to premalignancy and/or malignancy ...
Nurina Febriyanti Ayuningtyas +7 more
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ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies
Molecular Neurodegeneration, 2022 Alzheimer’s disease (AD) is the most common cause of dementia worldwide, and its prevalence is rapidly increasing due to extended lifespans. Among the increasing number of genetic risk factors identified, the apolipoprotein E ( APOE ) gene remains the ...
Ana-Caroline Raulin +5 more
semanticscholar +1 more source
Pathophysiology, 2022 Cytokines are expressed by various cells after several stimuli such as surgical tissue damage, producing a systemic inflammatory response (SIR). C-reactive protein (CRP) is used extensively in clinical practice after operative injury, but proinflammatory
Cristina Vila Zárate +7 more
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Seminars in Interventional Radiology, 2005 Chronic venous insufficiency and varicose veins are among the most prevalent medical problems in the adult population. Historically, our understanding of venous reflux disease focused upon the anatomical mechanisms of valvular incompetence. More recent investigations into the cellular and molecular aspects of venous insufficiency have shown that the ...
openaire +2 more sources