Results 41 to 50 of about 940,129 (290)

Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives

International Journal of Molecular Sciences, 2020
Stroke is the second leading cause of death and a major contributor to disability worldwide. The prevalence of stroke is highest in developing countries, with ischemic stroke being the most common type.
Diji Kuriakose, Zhicheng Xiao
semanticscholar   +1 more source

Small Fiber Neuropathy in Sarcoidosis

Pathophysiology, 2021
Sarcoidosis (SC) is a granulomatous disease of an unknown origin. The most common SC-related neurological complication is a small fiber neuropathy (SFN) that is often considered to be the result of chronic inflammation and remains significantly ...
Natalia Gavrilova, Anna Starshinova, Yulia Zinchenko, Dmitry Kudlay, Valeria Shapkina, Anna Malkova, Ekaterina Belyaeva, Maria Pavlova, Piotr Yablonskiy, Yehuda Shoenfeld   +9 more
doaj   +1 more source

Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions

Circulation Research, 2022
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and mortality. This review article focuses on the epidemiology, cause, mechanisms of injury, current treatment strategies, and future research directions of ICH. Incidence
J. Magid-Bernstein, R. Girard, S. Polster, Abhinav Srinath, Sharbel Romanos, I. Awad, Lauren H. Sansing   +6 more
semanticscholar   +1 more source

Dysregulated Sulfide Metabolism in Multiple Sclerosis: Serum and Vascular Endothelial Inflammatory Responses

Pathophysiology, 2022
Multiple sclerosis (MS) is a leading cause of neurodegenerative disability in younger individuals. When diagnosed early, MS can be managed more effectively, stabilizing clinical symptoms and delaying disease progression.
Pooja Veerareddy, Nhi Dao, Jungmi W. Yun, Karen Y. Stokes, Elizabeth Disbrow, Christopher G. Kevil, Urska Cvek, Marjan Trutschl, Philip Kilgore, Murali Ramanathan, Robert Zivadinov, Jonathan S. Alexander   +11 more
doaj   +1 more source

Pathophysiology, diagnosis, and management of endometriosis

British medical journal, 2022
Endometriosis affects approximately 190 million women and people assigned female at birth worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of endometrial-like tissue outside the uterus, which in many patients is ...
A. Horne, S. Missmer
semanticscholar   +1 more source

Biomolecular Mechanisms of Autoimmune Diseases and Their Relationship with the Resident Microbiota: Friend or Foe?

Pathophysiology, 2022
The use of innovative approaches to elucidate the pathophysiological mechanisms of autoimmune diseases, as well as to further study of the factors which can have either a positive or negative effect on the course of the disease, is essential.
Skender Topi, Lucrezia Bottalico, Ioannis Alexandros Charitos, Marica Colella, Marina Di Domenico, Raffaele Palmirotta, Luigi Santacroce   +6 more
doaj   +1 more source

Early and Long-Term Results of Simultaneous and Staged Revascularization of Coronary and Carotid Arteries

Pathophysiology
Background: Carotid artery disease is prevalent among patients with coronary heart disease. The concomitant severe lesions in the carotid and coronary arteries may necessitate either simultaneous or staged revascularization involving coronary bypass and ...
Elena Golukhova, Igor Sigaev, Milena Keren, Inessa Slivneva, Bektur Berdibekov, Nina Sheikina, Olga Kozlova, Valery Arakelyan, Irina Volkovskaya, Tatiana Zavalikhina, Susanna Avakova   +10 more
doaj   +1 more source

Molecular Mimicry between SARS-CoV-2 and Human Endocrinocytes: A Prerequisite of Post-COVID-19 Endocrine Autoimmunity?

Pathophysiology, 2022
Molecular mimicry between human and microbial/viral/parasite peptides is common and has long been associated with the etiology of autoimmune disorders provoked by exogenous pathogens.
Leonid P. Churilov, Muslimbek G. Normatov, Vladimir J. Utekhin   +2 more
doaj   +1 more source

Sepsis—Pathophysiology and Therapeutic Concepts

Frontiers in Medicine, 2021
Sepsis is a life-threatening condition and a global disease burden. Today, the heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated host response to infection, with renewed emphasis on immune pathophysiology. Despite all
D. Jarczak, S. Kluge, A. Nierhaus
semanticscholar   +1 more source

Biophysical Mechanisms of Vaginal Smooth Muscle Contraction: The Role of the Membrane Potential and Ion Channels

Pathophysiology
The vagina is an essential component of the female reproductive system and is responsible for providing female sexual satisfaction. Vaginal smooth muscle contraction plays a crucial role in various physiological processes, including sexual arousal ...
Chitaranjan Mahapatra, Ravinder Kumar
doaj   +1 more source