Results 81 to 90 of about 2,455,447 (352)

Shortest paths between shortest paths

open access: yesTheoretical Computer Science, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marcin Kaminski 0001   +2 more
openaire   +3 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

[r,s,t]-colourings of paths [PDF]

open access: yesOpuscula Mathematica, 2007
The concept of \([r,s,t]\)-colourings was recently introduced by Hackmann, Kemnitz and Marangio [A. Kemnitz, M. Marangio, \([r,s,t]\)-Colorings of Graphs, Discrete Math., to appear] as follows: Given non-negative integers \(r\), \(s\) and \(t\), an \([r ...
Marta Salvador Villà, Ingo Schiermeyer
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Enumeration of Generalised Directed Lattice Paths in a Strip [PDF]

open access: yes, 2019
PhD thesisThis thesis is about the enumeration of two models of directed lattice paths in a strip. The first problem considered is of path diagrams formed by Dyck paths and columns underneath it, counted with respect to the length of the paths and the ...
KHALID, ANUM
core  

La performance del sistema educativo argentino en las últimas décadas

open access: yesAnálisis, 2017
In the context of expansion and multiple transformations of the Argentine educational system, overfly discussions on institutional expansion, the evolution of the school population and samples of a system designed to generate greater inclusion. The aim of
Analía Otero, Agustina Córica
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Generation of transport paths in fractured porous media

open access: yes, 2017
In this article, a method for generation of transport paths in combined equivalent porous media / discrete fracture network computational meshes is proposed as an alternative to a particle tracking method. It is based on a computation of the functional
Říha Jakub, Královcová Jiřina
core   +1 more source

A logic of graph conditions extended with paths [PDF]

open access: yes, 2016
In this paper we tackle the problem of extending the logic of nested graph conditions with paths. This means, for instance, that we may state properties about the existence of paths between some given nodes.
Lambers, Leen   +3 more
core   +2 more sources

The Crossing Numbers of Join Products of All 5-Vertex Graphs with Discrete Graphs, Paths and Cycles

open access: yesMathematics
This paper investigates crossing numbers of join products involving all non-isomorphic graphs of order five and the graph families Dn, Pn, and Cn. By systematically examining all 34 graphs of order five, we establish a unified classification of 102 ...
Jana Fortes, Mária Timková
doaj   +1 more source

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