Results 61 to 70 of about 2,163,430 (288)

Optimal parametrizations of adiabatic paths

open access: yes, 2010
The parametrization of adiabatic paths is optimal when tunneling is minimized. Hamiltonian evolutions do not have unique optimizers. However, dephasing Lindblad evolutions do. The optimizers are simply characterized by an Euler-Lagrange equation and have
E. B. Davies   +8 more
core   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

La performance del sistema educativo argentino en las últimas décadas

open access: yesAnálisis, 2017
In the context of expansion and multiple transformations of the Argentine educational system, overfly discussions on institutional expansion, the evolution of the school population and samples of a system designed to generate greater inclusion. The aim of
Analía Otero, Agustina Córica
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Sabato's spiritual crisis: The way from science to literature [PDF]

open access: yesSinteze, 2017
The paper is entirely dedicated to the period of spiritual crisis in the life of Argentine writer Ernesto Sabato. In the introduction are stated basic biographical details from the life of the writer for the purpose of further elaboration of specific ...
Čanović Ana R.
doaj  

Induced Subgraph Saturated Graphs

open access: yesTheory and Applications of Graphs, 2016
A graph $G$ is said to be \emph{$H$-saturated} if $G$ contains no subgraph isomorphic to $H$ but the addition of any edge between non-adjacent vertices in $G$ creates one.
Craig Tennenhouse
doaj   +1 more source

Hard paths, soft paths or no paths? Cross-cultural perceptions of water solutions [PDF]

open access: yesHydrology and Earth System Sciences, 2014
In this study, we examine how development status and water scarcity shape people's perceptions of "hard path" and "soft path" water solutions. Based on ethnographic research conducted in four semi-rural/peri-urban sites (in Bolivia, Fiji, New Zealand ...
A. Wutich   +5 more
doaj   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer   +3 more
wiley   +1 more source

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