Results 41 to 50 of about 42,675 (259)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Path-cycle Ramsey numbers

open access: yesDiscrete Mathematics, 1974
AbstractRecently, Ramsey numbers have been obtained for several classes of graphs. In particular, they have been studied for graphs of low order, pairs of paths, pairs of cycles, and for a star and a path. In this paper, the Ramsey numbers are obtained for all path-cycle pairs.
Ralph J. Faudree   +3 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Edge ideals and DG algebra resolutions

open access: yesLe Matematiche, 2015
Let R = S/I where S = k[T_1, . . . , T_n] and I is a homogeneous ideal in S. The acyclic closure R<Y> of k over R is a DG algebra resolution obtained by means of Tate’s process of adjoining variables to kill cycles.
Adam Boocher   +4 more
doaj  

Simple Paths and Cycles of Directed Graph for Stock Trading Network Based on STP

open access: yesJournal of Mathematics, 2022
The stock trading relationship of buyers and sellers in the stock market can be characterized by a directed graph. It is an important way to study stock trading network through simple directed paths and cycles.
Xiaolong Liu, Li Ma
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Γ-independent dominating graphs of paths and cycles [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST)
A set D of vertices in a graph G is an independent dominating set if D is a set of pairwise nonadjacent vertices of G such that every vertex of G not in D is adjacent to at least one vertex in D.
Roongrat Samanmoo   +1 more
doaj  

Microalgae growth in ultra-thin steady-state continuous photobioreactors: assessing self-shading effects

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
To disclose the net effect of light on microalgal growth in photobioreactors, self-shading and mixing-induced light–dark cycles must be minimized and discerned from the transient phenomena of acclimation.
Alberto Saccardo   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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