Results 41 to 50 of about 54,765 (253)

Roman domination number on cardinal product of paths and cycles

open access: yesCroatian Operational Research Review, 2015
In this paper, the authors have determined certain upper and lower bounds for Roman domination numbers on cardinal products for any two graphs and some exact values for the cardinal product of paths and cycles.
Antoaneta Klobučar, Ivona Puljić
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Edge magic total labeling of lexicographic product C4(2r+1) o ~K2 cycle with chords, unions of paths, and unions of cycles and paths

open access: yesIndonesian Journal of Combinatorics, 2018
An edge magic total (EMT) labeling of a graph G = (V, E) is a bijection from the set of vertices and edges to a set of numbers defined by λ : V ∪ E → {1, 2, ..., ∣V∣ + ∣E∣} with the property that for every xy ∈ E, the weight of xy equals to a constant k,
Inne Singgih
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Monochromatic transversal game on tight paths and tight cycles

open access: yesCadernos Cajuína
We explore in this paper a combinatorial maker-breaker game, proposed by Mendes et al. in 2020, named -monochromatic transversal game. Such a game, which is defined over a hypergraph, is played by two competitors, Alice and Bob, that alternately take ...
Wilder Pinto Mendes   +6 more
doaj   +1 more source

Extrema property of the k-ranking of directed paths and cycles

open access: yesAKCE International Journal of Graphs and Combinatorics, 2016
A k-ranking of a directed graph G is a labeling of the vertex set of G with k positive integers such that every directed path connecting two vertices with the same label includes a vertex with a larger label in between.
Breeanne Baker Swart   +3 more
doaj   +1 more source

The Crossing Numbers of Join Products of Paths and Cycles with Four Graphs of Order Five

open access: yesMathematics, 2021
The main aim of the paper is to establish the crossing numbers of the join products of the paths and the cycles on n vertices with a connected graph on five vertices isomorphic to the graph K1,1,3\e obtained by removing one edge e incident with some ...
Michal Staš
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Existence of Δλ-cycles and Δλ-paths [PDF]

open access: yes, 1988
A Cycle C of a graph G is called a Dλ-cycle if every component of G - V(C) has order less than λ A Dλ-path is defined analogously. Dλ-cycles and Dλ-paths were introduced by Veldman.
Broersma, H.J.; id_orcid
core   +1 more source

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