Results 91 to 100 of about 382,587 (364)

Evaluation of the Establishment of a Public and Patient Involvement and Engagement Group to Support Clinical Trials in Pakistan: Protocol for a Mixed-Methods Study [version 2; peer review: 2 approved]

Wellcome Open Research
Background Patient and public involvement and engagement (PPIE) in research is a collaboration between researchers, patients, and the public, enhancing research acceptability, relevance, and impact.
Monaza Khan, Shehla Farooq, Srinivas Murthy, Nikhat Ahmed, Saima Saleem, Adnan Masood, Shahnaz Zaman, Zahyd Shuja, Arishay Hussaini, Timo Tolppa, Arjen M Dondorp, Madiha Hashmi   +11 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Making Patient Engagement a Reality [PDF]

The Patient - Patient-Centered Outcomes Research, 2017
Patients are increasingly recognised as the true customers of healthcare. By providing insights and perspectives, patients can help the wider healthcare community better understand their needs and ultimately enhance the value of healthcare solutions being developed.
openaire   +2 more sources

Questioning patient engagement: research scientists’ perceptions of the challenges of patient engagement in a cardiovascular research network

, 2017
Sandra L Carroll,1 Gayathri Embuldeniya,1 Julia Abelson,2 Michael McGillion,1 Alexandre Berkesse,3 Jeff S Healey4 1Faculty of Health Sciences, School of Nursing, McMaster University, Hamilton, ON, 2Faculty of Health Sciences, Health Research Methods ...
McGillion M, Carroll SL, Abelson J, Healey JS, Embuldeniya G, Berkesse A   +5 more
core  

Patient Engagement and Co-creation in Healthcare Services: A Scoping Review

Objective: The objective of this review was to find literature related to the concepts of patient engagement and co-creation in healthcare services and identify models and/or frameworks that combined these concepts.
Thiruppavai Sundaramurthi, Smita Mathews, Satish Mahajan, Ella Bermudez, Mathews, Smita, Mahajan, Satish M, Bermudez, Ella, Sundaramurthi, Thiruppavai   +7 more
core   +1 more source

Engagement, empowerment and patient generated health data

, 2017
This thesis examines patient generated health data in the context of healthcare services where information asymmetry traditionally enshrined the doctor as all-powerful and the patient as a passive recipient. Through vignette-led interviews and a clinical
Burns, Kara R.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Wonderings to research questions: Engaging patients in long COVID research prioritization within a learning health system

Learning Health Systems
Background An integral component of research within a learning health system is patient engagement at all stages of the research process. While there are well‐defined best practices for engaging with patients on predetermined research questions, there is
Ann Blair Kennedy, Ariana Mitcham, Katherine Parris, Faith Albertson, Luis Sanchez Ferrer, Conor O'Boyle, Maushmi K. Patel, Tracey Gartner, Amy M. Broomer, Evan Katzman, Jeanette Coffin, Jennifer T. Grier, Nabil Natafgi   +12 more
doaj   +1 more source

Increasing patient engagement in healthcare service design: a qualitative evaluation of a co-design programme in New Zealand

, 2017
The Health & Quality Safety Commission New Zealand commissioned Ko Awatea, an innovation and improvement centre, to deliver a co-design programme to nine teams of healthcare providers.
Brooke Hayward, Hayward, Patricia, Lynne Margaret Maher, Maher, Lynne Margaret, Dr., Hayward, Brooke, Walsh, Chris, Dr, Patricia Hayward, Lynne Maher, Chris Walsh   +8 more
core   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source