Results 121 to 130 of about 16,806,898 (405)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Providing Feedback Following Leadership Walkrounds is Associated with Better Patient Safety Culture, Higher Employee Engagement and Lower Burnout [PDF]

, 2017
Background There is a poorly understood relationship between Leadership WalkRounds (WR) and domains such as safety culture, employee engagement, burnout and work-life balance.
Adair, Kathryn C., Bogan, Brittany, Frankel, Allan S., Frankel, Terru Christensen, Jamal, Maleek, Leonard, Michael W., Magnus, Brooke E., Proulx, Joshua, Schwendimann, Rene, Sexton, J. Bryan, Watson, Sam R.   +10 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Patient Engagement—What Works?

Journal of Ambulatory Care Management, 2012
The recent focus on patient engagement acknowledges that patients have an important role to play in their own health care. This includes reading, understanding and acting on health information (health literacy), working together with clinicians to select appropriate treatments or management options (shared decision making), and providing feedback on ...
openaire   +2 more sources

The local environment matters: Evidence from digital healthcare services for patient engagement [PDF]

, 2023
Ruba Aljafari, Franck Soh, Pankaj Setia, Ritu Agarwal   +3 more
openalex   +1 more source

Patient Engagement and Opinions of a Medication Assisted Treatment Program for Opioid Use Disorder: A Qualitative Assessment [PDF]

, 2020
Introduction: Opioid use disorder is widely regarded as a national health epidemic. Stephen Klein Wellness Center 6as started a Medication-Assisted Treatment (MAT) program to help combat this epidemic- a program that is unique in that it does not require
Wagoner, Sarah, Weinstein, MD, Lara
core   +1 more source

A new scale to assess the therapeutic relationship in community mental health care: STAR [PDF]

, 2007
Background. No instrument has been developed specifically for assessing the clinician-patient therapeutic relationship (TR) in community psychiatry. This study aimed to develop a measure of the TR with clinician and patient versions using psychometric ...
Catty, Jocelyn, Hansson, Lars,, Lund University., McCabe, Rosemarie, McGuire-Snieckus, Rebecca, Priebe, Stefan   +5 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Best Practices Guidelines for the Engagement of People With Lived Experience and Family Members in Mental Health and Substance Use Health Research: A Modified Delphi Consensus Study

Health Expectations
Introduction People with lived experience of mental health and/or substance use conditions and their families (PWLE) are increasingly engaged in research, yet rigorous guidelines for engagement are lacking.
Lisa D. Hawke, Wuraola Dada‐Phillips, Hajar Seiyad, Josh Orson, Lianne Goldsmith, Susan Conway, Adam Jordan, Natasha Y. Sheikhan, Melissa Hiebert, Sean Kidd, Kerry Kuluski   +10 more
doaj   +1 more source

A review and synthesis of frameworks for engagement in health research to identify concepts of knowledge user engagement

BMC Medical Research Methodology, 2019
Background Engaging those who influence, administer and/or who are active users (“knowledge users”) of health care systems, as co-producers of health research, can help to ensure that research products will better address real world needs. Our aim was to
Janet E. Jull, Laurie Davidson, Rachel Dungan, Tram Nguyen, Krista P. Woodward, Ian D. Graham   +5 more
doaj   +1 more source