Results 41 to 50 of about 296,381 (341)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Measuring person-centred care in the mission, vision, and core value statements of Canadian healthcare organizations

open access: yesBMC Health Services Research
Background Person-centred care (PCC) has been shown to improve health outcomes. The inclusion and incorporation of person-centredness in care has been a growing priority for healthcare organizations across Canada.
Iqmat Iyiola   +5 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Developing An Analytic Approach to Understanding the Patient Care Experience

open access: yesJournal of Patient Experience, 2016
The amount of data available to health-care institutions regarding the patient care experience has grown tremendously. Purposeful approaches to condensing, interpreting, and disseminating these data are becoming necessary to further understand how ...
Mary Kate Springman MHA   +3 more
doaj   +1 more source

Variation in parental experiences with their child’s hospitalization over the COVID-19 pandemic

open access: yesJournal of Patient-Reported Outcomes, 2023
Background Hospitals and healthcare workers have been greatly impacted by the COVID-19 pandemic. The potential impacts upon the patient experience have been less documented, particularly in the pediatric setting.
Kyle A. Kemp   +3 more
doaj   +1 more source

Fostering Bilateral Patient-Clinician Engagement in Active Self-Tracking of Subjective Experience [PDF]

open access: yes, 2018
In this position paper we describe select aspects of our experience with health-related self-tracking, the data generated, and processes surrounding those. In particular we focus on how bilateral patient-clinician engagement may be fostered by the combination of technology and method.
arxiv   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Developing an Effective and Automated Patient Engagement Estimator for Telehealth: A Machine Learning Approach [PDF]

open access: yesarXiv, 2020
We discuss MET, a learning-based algorithm proposed for perceiving a patient's level of engagement during telehealth sessions. We leverage latent vectors corresponding to Affective and Cognitive features frequently used in psychology literature to understand a person's level of engagement in a semi-supervised GAN-based framework.
arxiv  

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