Results 141 to 150 of about 196,815 (248)

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules. [PDF]

Immun Inflamm Dis
Sharma M, Wagh P, Shinde T, Trimbake D, Tripathy AS.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Study on differentially expressed genes and pattern recognition receptors in osteoporosis based on bioinformatics analysis. [PDF]

Sci Rep
Mao S, Wang Y, Gu M, Liu K, Ma J, Miao J, Zhao F.   +6 more
europepmc   +1 more source

Corrigendum to: Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria. [PDF]

Zoonoses, 2023
Fisher JR, Chroust ZD, Onyoni F, Soong L.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Nanocarrier-Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy. [PDF]

Adv Healthc Mater
Ismail EA, Nyandoro VO, Omolo CA, Govender T.   +3 more
europepmc   +1 more source

Immunomodulators secreted from parasitic helminths act on pattern recognition receptors. [PDF]

Front Parasitol, 2022
Tsubokawa D.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Sensing danger in the islet: the roles of pattern recognition receptors in β cells and type 1 diabetes. [PDF]

Front Immunol
Tong L, Tu Y, Huang S, Zheng P.
europepmc   +1 more source

Microbe-associated molecular pattern recognition receptors have little effect on endophytic Arabidopsis thaliana microbiome assembly in the field. [PDF]

Front Plant Sci, 2023
Oldstone-Jackson C, Huang F, Bergelson J.   +2 more
europepmc   +1 more source