Results 71 to 80 of about 8,051 (168)

Expression of unfolded protein response markers in the pheochromocytoma with Waardenburg syndrome: a case report

BMC Endocrine Disorders, 2020
Background It is clinically emergent to further understand the pathological mechanism to advance therapeutic strategy for endocrine tumors. A high amount of secretory protein with tumorigenic triggers are thought to induce unfolded protein response in ...
Shuhei Morita, Ken Takeshima, Hiroyuki Ariyasu, Yasushi Furukawa, Shohei Kishimoto, Tomoya Tsuji, Shinsuke Uraki, Hiroyuki Mishima, Akira Kinoshita, Yuichi Takahashi, Hidefumi Inaba, Hiroshi Iwakura, Hiroto Furuta, Masahiro Nishi, Asako Doi, Shin-ichi Murata, Koh-ichiro Yoshiura, Takashi Akamizu   +17 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, Volume 20, Issue 5, Page 1185-1201, May 2026.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Wnt1 Positively Regulates CD36 Expression via TCF4 and PPAR-γ in Macrophages

Cellular Physiology and Biochemistry, 2015
Background: Scavenger receptors including CD36 control the phagocytosis of oxidized low-density lipoprotein and play an important role in macrophage physiology, but the underlying molecular mechanism by which CD36 is regulated in macrophages or during ...
Shuai Wang, Zewei Sun, Xi Zhang, Zhenwei Li, Mingjie Wu, Wenting Zhao, Houhong Wang, Ting Chen, Hui Yan, Jianhua Zhu   +9 more
doaj   +1 more source

Corrigendum to “Key basic helix–loop–helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development” [Dev. Biol. 316 (2008) 510–523]

Developmental Biology, 2008
Corrigendum Corrigendum to “Key basic helix–loop–helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development” [Dev. Biol. 316 (2008) 510–523] Hiromichi Nakazaki, Anvesh C. Reddy, Barbara L. Mania-Farnell, Yueh-Wei Shen, Shunsuke Ichi, Christopher McCabe, David George, David G.
Nakazaki, Hiromichi, Reddy, Anvesh C., Mania-Farnell, Barbara L., Shen, Yueh-Wei, Ichi, Shunsuke, McCabe, Christopher, George, David, McLone, David G., Tomita, Tadanori, Mayanil, C.S.K.   +9 more
openaire   +1 more source

Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage

The Scientific World Journal, 2007
Although it is well established that transgenic manipulation of mammalian neural crest-related gene expression and microsurgical removal of premigratory chicken and Xenopus embryonic cardiac neural crest progenitors results in a wide spectrum of both ...
Paige Snider, Michael Olaopa, Anthony B. Firulli, Simon J. Conway   +3 more
doaj   +1 more source

FOXN1: a master regulator gene of thymic epithelial development programme

Frontiers in Immunology, 2013
T cell ontogeny is a sophisticated process, which takes place within the thymus through a series of well-defined discrete stages. The process requires a proper lympho-stromal interaction.
Rosa eRomano, Loredana ePalamaro, Anna eFusco, Giuliana eGiardino, Vera eGallo, Luigi eDel Vecchio, Claudio ePignata   +6 more
doaj   +1 more source

Additional file 4: Figure S4. of Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

, 2017
DUX4 and PAX7 are expressed in distinct cell types during myogenic differentiation of hiPSC-mosaic 1 with the short D4Z4 array. A, B and C) Images of hiPSC-mosaic 1 with the short D4Z4 array from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4. Arrows indicate representative DUX4 positive nuclei counted. (DOCX 5052 kb)
Premi Haynes, Kernan, Kelly, Suk-Lin Zhou, Miller, Daniel   +3 more
openaire   +1 more source

Additional file 7: Figure S7. of Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

, 2017
DUX4 is not expressed in PAX7 positive myocytes in control human ES cells. A and B) Images of hESC-cntrl myocytes from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4 and utilized to quantify the number of DUX4 and PAX7 positive cells. (DOCX 1665 kb)
Premi Haynes, Kernan, Kelly, Suk-Lin Zhou, Miller, Daniel   +3 more
openaire   +1 more source

Additional file 6: Figure S6. of Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

, 2017
DUX4 and PAX7 are expressed in distinct cell types during myogenic differentiation of hiPSC-mosaic 2 with the short D4Z4 array. A, B, C, D and E) Images of hiPSC-mosaic 2 with the short D4Z4 array from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4. Arrows indicate representative DUX4 positive nuclei counted.
Premi Haynes, Kernan, Kelly, Suk-Lin Zhou, Miller, Daniel   +3 more
openaire   +1 more source

Additional file 3: Figure S3. of Expression patterns of FSHD-causing DUX4 and myogenic transcription factors PAX3 and PAX7 are spatially distinct in differentiating human stem cell cultures

, 2017
DUX4 is not expressed in PAX7 positive myocytes in hiPSC-mosaic 1 with the long D4Z4 array. A, B, and C) Images of hiPSC-mosaic 1 long myocytes from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4 and utilized to quantify the number of DUX4 and PAX7 positive cells. (DOCX 4880 kb)
Premi Haynes, Kernan, Kelly, Suk-Lin Zhou, Miller, Daniel   +3 more
openaire   +1 more source