Results 81 to 90 of about 8,051 (168)
Human iPS isogenic clones hiPSC-mosaic 2 with long and short D4Z4 array differentiate into skeletal myocytes with progressive expression of myogenic markers characteristic of early, middle, and late stages of myogenesis. Bright field images of A) hiPSC-mosaic2-long and D) hiPSC-mosaic2-short at the various stages of differentiation.
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DUX4 and PAX7 are expressed in distinct cell types during myogenic differentiation of human ES cells with FSHD. A, B, C, D, E and F) Images of hESC-FSHD from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4. Arrows indicate representative DUX4 positive nuclei counted. (DOCX 6109 kb)
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Human ES cells differentiate into skeletal myocytes with progressive expression of myogenic markers characteristic of early, middle, and late stages of myogenesis. Bright field images of A) HESC-Cntrl and D) FSHD at the various stages of differentiation.
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DUX4 is not expressed in PAX7 positive myocytes in hiPSC-mosaic 2 with the long D4Z4 array. A and B) Images of hiPSC-mosaic 2 long myocytes from D40 of the differentiation protocol stained with antibodies to both PAX7 and DUX4 and utilized to quantify the number of DUX4 and PAX7 positive cells. (DOCX 1755 kb)
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Melanin is an amino acid derivative produced by melanocyte through a series of enzymatic reactions using tyrosinase as substrate. Human skin and hair color is also closely related to melanin, so understanding the mechanisms and proteins that produce ...
Feifei Wang +15 more
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Injected matrix stimulates myogenesis and regeneration of mouse skeletal muscle after ischaemic injury [PDF]
Biomaterial-guided regeneration represents a novel approach for the treatment of myopathies. Revascularisation and the intramuscular extracellular matrix are important factors in stimulating myogenesis and regenerating muscle damaged by ischaemia.
D Kuraitis +15 more
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Generation of a conditional loxP allele of the Pax3 transcription factor that enables selective deletion of the homeodomain [PDF]
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Core Transcription Factors Promote Induction of PAX3-Positive Skeletal Muscle Stem Cells
The use of adult skeletal muscle stem cells (MuSCs) for cell therapy has been attempted for decades, but still encounters considerable difficulties. MuSCs derived from human induced pluripotent stem cells (hiPSCs) are promising candidates for stem cell therapy to treat Duchenne muscular dystrophy (DMD).
openaire
Genetic architecture of craniofacial morphogenesis: roles of <i>PAX3</i>, <i>PAX7</i>, and <i>PAX9</i>. [PDF]
Wang K, Li N, Liu W, Li YG, Ren F.
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