Results 91 to 100 of about 20,380 (169)

The Role of Pax6 in Brain Patterning.

The Tohoku Journal of Experimental Medicine, 2001
Pax6 g ene encodes a transcription factor that plays a pivotal role in various aspects of brain development. Here I review the molecular and cellular mechanisms of how the early brain is patterned, and introduce recent studies on the role of Pax6 in brain patterning, neuronal specification, neuronal migration and axonal extension.
openaire   +3 more sources

PAX6–WNK2 Axis Governs Corneal Epithelial Homeostasis

Investigative Ophthalmology & Visual Science
Limbal stem/progenitor cells (LSCs) continuously proliferate and differentiate to replenish the corneal epithelium and play a vital role in corneal function and normal vision. A previous study revealed that paired box 6 (PAX6) is a master transcription factor involved in determining the fate of corneal epithelial cells (CECs).
Zhu, Liqiong, Chen, Chaoqun, Wu, Siqi, Guo, Huizhen, Li, Lingyu, Wang, Li, Liu, Dongmei, Zhan, Yu, Du, Xinyue, Liu, Jiafeng, Tan, Jieying, Huang, Ying, Mo, Kunlun, Lan, Xihong, Ouyang, Hong, Yuan, Jin, Chen, Xiangjun, Ji, Jianping   +17 more
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PAX6 wt Allele [PDF]

, 2020
openaire   +1 more source

Kongenitale Aniridie oder PAX6-Syndrom? [PDF]

Der Ophthalmologe, 2014
B. Käsmann-Kellner, B. Seitz
openaire   +1 more source

Cooperation of Transcription Factor PAX6 with Chromatin-Remodeling Complex BAF During Embryonic Development in Mammals. [PDF]

Cell Mol Neurobiol
Azieva A, Vasilyeva T, Maksimenko O, Davydenko K, Zinchenko R, Marakhonov A.   +5 more
europepmc   +1 more source

Aberrant maintenance of developmental transcription factor PAX6 promotes neuronal cell death via JNK3 signaling. [PDF]

Cell Death Dis
Kim JY, An MJ, Kim J, Kim CH, Park Y, Shin GS, Lee HM, Jo AR, Kim MJ, Hwangbo Y, Hong TK, Kim JT, Choi U, Kim JW.   +13 more
europepmc   +1 more source

Essential Role of CD63 in Maintaining Corneal Epithelial Identity in the Human Limbus. [PDF]

Invest Ophthalmol Vis Sci
Sasamoto Y, Suzuki K, Sato S, Lee CAA, Martin G, Ksander BR, Frank MH, Frank NY.   +7 more
europepmc   +1 more source

PAX6 Deficiency Compromises the Ability of Limbal Epithelial Stem Cells to Properly Differentiate Into Mature Corneal Epithelial Cells. [PDF]

Invest Ophthalmol Vis Sci
Foroozandeh P, Kaplan N, Qi X, Yang W, Chen X, Lee SK, Ren Z, Lavker RM, Kume T, Peng H.   +9 more
europepmc   +1 more source

Paired box 6 (PAX6) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

β-ionone synergizes with 5-Fluorouracil to inhibit gastric cancer progression through PAX6-mediated cell cycle arrest. [PDF]

BMC Cancer
Li J, Wang FL, Yang TT, Yu XL, Cai QR, Ye QN, Zhang S, Wang Q, Dong HW, Liu JR.   +9 more
europepmc   +1 more source