Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker.
The transcription factor Pax6 is an important regulator of development and cell differentiation in various organs. Thus, Pax6 was shown to promote neural development in the cerebral cortex and spinal cord, and to control pancreatic endocrine cell genesis.
Zeeshan Ahmad +3 more
doaj +1 more source
Expression and interaction mechanism of PAX6 in human non-small cell lung cancer
Background and purpose: The transcription factor PAX6 is primarily expressed in embryos. PAX6 is also expressed in several tumors and plays oncogenic or tumor suppressor role. This study aimed to investigate the expression of PAX 6 in non-small cell lung
熊安洲, 陈菁, 曹艳, 胡小萍
doaj
Molecular analysis of the PAX6 gene for aniridia and congenital cataracts in Tunisian families [PDF]
Manèl Chograni +4 more
openalex +1 more source
Similarities in DSG1 and KRT3 Downregulation through Retinoic Acid Treatment and PAX6 Knockdown Related Expression Profiles: Does PAX6 Affect RA Signaling in Limbal Epithelial Cells? [PDF]
Lorenz Latta +9 more
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Pax6-dependent mechanisms in mammalian corticogenesis
Pax6 is a key transcription factor involved in the organogenesis of the eye, pancreas, and brain. In developing cortex, Pax6 has been implicated to play a role in regionalization, neurogenesis, layer formation, and axonal path finding. The study of whether Pax6 regulates key processes in corticogenesis and brain functioning has been hindered by a ...
openaire +3 more sources
Functional Characteristics of Diverse PAX6 Mutations Associated with Isolated Foveal Hypoplasia [PDF]
Itsuka Matsushita +8 more
openalex +1 more source
Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer [PDF]
Yury Kiselev +10 more
openalex +1 more source
Pax6Is Required at the Telencephalic Pallial–Subpallial Boundary for the Generation of Neuronal Diversity in the Postnatal Limbic System [PDF]
Laura Cocas +8 more
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Novel functions of LHX2 and PAX6 in the developing telencephalon revealed upon combined loss of both genes [PDF]
Geeta Godbole +3 more
openalex +1 more source
A novel 11p13 microdeletion encompassing PAX6 in a Chinese Han family with aniridia, ptosis and mental retardation [PDF]
Ping Hu +7 more
openalex +1 more source

