Results 91 to 100 of about 22,874 (232)
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Take Pax6 for a Cortical 6-Pack
PLOS Biology, 2015 This synopsis examines the implications of a new study that imposes primate-like expression of the transcription factor Pax6 on the developing mouse cortex and finds evidence of primate-like proliferation of neuronal progenitors.
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Developmental Dynamics, Volume 255, Issue 6, Page 533-547, June 2026.Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa +2 more
wiley +1 more source
A rare case of congenital aniridia with an unusual run-on mutation in PAX6 gene
Indian Journal of Ophthalmology, 2022 Ria Ratna +5 more
doaj +1 more source
Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci
Cell Proliferation, Volume 59, Issue 6, June 2026.To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
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Cell Proliferation, Volume 59, Issue 6, June 2026.Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
Scientific ReportsThe paired box 6 (Pax6) gene encodes a highly conserved transcription factor, involved in the development of eyes, brain, and endocrine glands. Homozygous loss of Pax6 resulted in neonatal death in mice, plus loss of eyes and malformation of cerebral ...
Bichao Zhang +5 more
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Phenotypic variation in a four-generation family with aniridia carrying a novel PAX6 mutation [PDF]
, 2017 Grace M. Wang +3 more
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Histopathology, Volume 88, Issue 7, Page 1315-1323, June 2026.PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert +5 more
wiley +1 more source
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on PAX6 (paired box 6), with data on DNA, on the protein encoded, and where the gene is implicated.
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