Results 101 to 110 of about 5,951 (176)

Translational Modeling of Gut Microbiome-Mediated Drug Metabolism: A Case Example of Sulfasalazine. [PDF]

CPT Pharmacometrics Syst Pharmacol
Cheng L, Cai J, Auster A, Cho S, Keir M, Rhee H, Kapili B, Shalon D, Ning M.   +8 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling and Therapeutic Drug Monitoring for Ertapenem Dose Optimization in Hypoalbuminemia Elderly Patients. [PDF]

Drug Des Devel Ther
Du X, Dong Z, Li Y, Wu Y, Wu H.
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Antiretroviral-BTK Inhibitor Interactions and Provide Recommendations for Co-Administration Regimens. [PDF]

Pharmaceutics
Chen L, Wang X, Li L, Yang Y, Liu Y, Chen W.   +5 more
europepmc   +1 more source

RENAsym, a quantitative systems toxicology platform model, designed to predict drug-induced kidney injury indicates polymyxin B and valproate overdose toxicity potential while simultaneously demonstrating acetaminophen and valproate safety at therapeutic levels. [PDF]

Toxicol Sci
Vallejo C, Bhargava P, Hamzavi N, McDaniel M, Lakhani VV, Qi T, Battista C, Clemens L, Shoda LKM, Kenz ZR, Tallapaka S, Gebremichael Y, Woodhead JL.   +12 more
europepmc   +1 more source

Mechanistic Physiologically Based Pharmacokinetic Modeling to Predict CYP3A4-Mediated Drug-Drug Interactions of Flumatinib as Both a Victim and a Perpetrator. [PDF]

Drug Des Devel Ther
Alifu M, Chu X, Zhu X, Mak WY, Zheng A, Pan C, He Q, Zhu X, Kuai Z, Xiang X.   +9 more
europepmc   +1 more source

A PBPK model for benzo(A)pyrene in the rat

European Journal of Pharmaceutical Sciences, 1996
D. Moir, A. Viau, I. Chu, F.C.P. Law, K. Krishnan   +4 more
openaire   +1 more source

Biomonitoring of bisphenol A, S, and F in urine samples from children in Finland. [PDF]

Environ Monit Assess
Poursafa P, Koponen J, Rantakokko P, Helotie I, Koivusalo M.   +4 more
europepmc   +1 more source

Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025. [PDF]

CPT Pharmacometrics Syst Pharmacol
Cordes H, Annaert P, Balazki P, Benamara S, Bonan RH, Butler A, Chenel M, Cui Y, Dallmann A, de Witte WEA, Demeester C, Feick D, Gattacceca F, Geci R, Gerebtzoff G, Gruber A, Guimarães M, Hamadeh A, Hanke N, Ibarra M, Ince I, Kanacher T, Kuepfer L, Mil F, Montaseri G, Nauwelaerts N, Proenca S, Schaller S, Schlender JF, Schneider ARP, Sjögren E, Solodenko J, Staab A, Vrenken P, Troisi C, Teutonico D.   +35 more
europepmc   +1 more source

Subject-Specific Whole-Lung CFPD Coupled with PBPK/PD to Predict Inhaled Bronchodilator Response in Asthmatic and Healthy Subjects. [PDF]

J Aerosol Sci
Rajaraman PK, Zhang X, Comellas AP, Hoffman EA, Lin CL.   +4 more
europepmc   +1 more source

Physiologically-Based Pharmacokinetic Model-Informed Labeling for Cariprazine Drug Interactions With CYP3A Inhibitors. [PDF]

CPT Pharmacometrics Syst Pharmacol
Riad MMH, Marroum P, Shebley M, Xiong H.
europepmc   +1 more source