Population Physiologically-Based Pharmacokinetic Modeling to Determine Ontogeny: A Quantitative Clinical Pharmacology Example in Pediatric Rare Disease. [PDF]
CPT Pharmacometrics Syst PharmacolCleary Y +4 more
europepmc +1 more source
An Integrated AIVIVE-PBPK-QIVIVE Framework with HTTK Validation for Probabilistic Risk Assessment of Neodymium Nitrate. [PDF]
Chem Res ToxicolWang N +9 more
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Application of New Approach Methodologies to Improve Oral Biopharmaceutic Assessments. [PDF]
PharmaceuticsGarcía MA +4 more
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Target-Controlled Infusion for Caesarean Delivery Under General Anesthesia: From Conventional Pharmacokinetic Models to Physiologically Based Pharmacokinetic Modeling. [PDF]
Life (Basel)Keresztes M +3 more
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Advancing Pharmacoequity in Low- and Middle-Income Countries via Model Informed Drug Development. [PDF]
Clin Transl SciEnzama H +5 more
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Dose Recommendation of Remimazolam Tosilate for General Anesthesia in Children and Adolescents: Synergistic Combination of PopPK and PBPK Approaches. [PDF]
PharmaceuticsLiang QY +4 more
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Albumin Levels Are Predictive of Cachexia-Induced Time-Dependent Clearance of Therapeutic Antibodies: A Physiologically Based Pharmacokinetic Model of Durvalumab. [PDF]
CPT Pharmacometrics Syst PharmacolProctor JR, Wong H.
europepmc +1 more source
From Population-Based PBPK to Individualized Virtual Twins: Clinical Validation and Applications in Medicine. [PDF]
J Clin MedGonçalves M, Barata P, Vale N.
europepmc +1 more source
Simulation of Imatinib Pharmacokinetics in pregnant women with chronic myeloid leukemia in the third trimester. [PDF]
Eur J Clin PharmacolMian P +8 more
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Virtual Bioequivalence Assessment of Long-Acting Injectable Suspensions Using PBPK Modeling: Part 2. Type I Error and Safe Space Analyses. [PDF]
AAPS JMorris NM +6 more
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