Results 171 to 180 of about 16,022 (277)

[[alternative]]Statistical Analysis on Environmental Risk Assessment Using Pharmacokinetic Physiologically-based Model [PDF]

open access: yes
計畫編號:NSC91-2118-M032-001研究期間:200208~200307研究經費:434,000[[sponsorship ...
陳主智
core  

Clinical Pharmacology Perspective on Direct‐To‐Subcutaneous Dosing of T Cell Engagers in Oncology First‐In‐Human Studies

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT While the subcutaneous (SC) route of administration (RoA) is more patient‐centric and cost‐effective than the intravenous (IV) RoA, the Switch‐to‐SC paradigm has been employed in oncology antibody drug development. T cell engagers (TCEs) are typically highly potent and efficacious at low doses, supporting their suitability for the Direct‐to‐SC
Wenlian Qiao   +3 more
wiley   +1 more source

A translational platform PBPK model for antibody disposition in the brain

open access: green, 2019
Hsueh-Yuan Chang   +3 more
openalex   +2 more sources

Human PBPK Modeling

open access: yes
This deliverable will report the final development of the human PBPK models developed within ...
openaire   +1 more source

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