Evaluation of the PK/PD Changes on MASLD-Related Population-An Example From Simultaneous Acetaminophen Parent-Metabolite PBPK/PD Modeling. [PDF]
Zhao S, Zhang L.
europepmc +1 more source
Interspecies extrapolation by physiologically based pharmacokinetic modeling [PDF]
Ghallab, Ahmed
core +1 more source
Strategy for Identifying Rational Sensitivity Analysis Using PBPK Modeling for Precipitant Drug-Drug Interaction Predictions. [PDF]
Taskar KS, Sharma P, Rowland Yeo K.
europepmc +1 more source
Physiologically Based Pharmacokinetic Modeling of Digoxin in Adult and Pediatric Patients with Heart Failure. [PDF]
Zhang Y, Liu Y, He H, Hao K.
europepmc +1 more source
Mechanism-Based Predictions of Local Tissue and Systemic Exposure for Drug Products Delivered Through the Female Reproductive Tract. [PDF]
Li X +10 more
europepmc +1 more source
Regional absorption of talinolol mediated by intestinal transporters: insights from PBPK modeling analysis. [PDF]
Ishida K +5 more
europepmc +1 more source
[177Lu]Lu-DOTA-TATE tumour and organ time-activity curves: prediction from a single-time-point [68Ga]Ga-DOTA-TATE PET/CT measurement. [PDF]
Vasić V +5 more
europepmc +1 more source
Development of physiologically based pharmacokinetic models for the bioaccumulation of persistent organic pollutants in marine mammals [PDF]
Weijs, L
core
Enhanced CYP2C19-mediated drug-drug interaction risk with escitalopram in geriatric populations. [PDF]
Byoun S +7 more
europepmc +1 more source
The Evolution and Future Directions of PBPK Modeling in FDA Regulatory Review. [PDF]
Li Y, Sun H, Zhang Z.
europepmc +1 more source

