Results 31 to 40 of about 9,895 (222)
Pharmaceutics, 2023 Enavogliflozin is a sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor approved for clinical use in South Korea. As SGLT2 inhibitors are a treatment option for patients with diabetes, enavogliflozin is expected to be prescribed in various ...
Min-Soo Kim +11 more
doaj +1 more source
Integrated multi-scale PBPK/PD model. [PDF]
, 2019 From left to right: Whole-body model (PBPK): The drug distribution is modelled using the PBPK approach at the level of the human whole-body. Integrated model (PBPK/PD): The integrated model encompasses the dose arriving from the whole-body PBPK model to ...
Jörg Lippert (124210) +7 more
core +1 more source
PBPK model reporting template for chemical risk assessment applications [PDF]
, 2020 Physiologically-based pharmacokinetic (PBPK) modeling analysis does not stand on its own for regulatory purposes but is a robust tool to support drug/chemical safety assessment.
PAINI Alicia +15 more
core +1 more source
Heang60/PBPK-of-Magic-Mushroom: Coding for PBPK of Magic Mushroom [PDF]
, 2021 No description ...
Kimheang, Kimheang Ya
core +1 more source
Current and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates [PDF]
, 2022 INTRODUCTION: There is a need for structured approaches to inform on pharmacotherapy in preterm neonates. With their proven track record up to regulatory acceptance, physiologically based pharmacokinetic (PBPK) modeling and simulation provide a ...
Allegaert, Karel +4 more
core +4 more sources
Drug Design, Development and Therapy, 2021 Muhammad Nasir Kalam,1 Muhammad Fawad Rasool,2 Faleh Alqahtani,3 Imran Imran,4 Asim Ur Rehman,1 Naveed Ahmed1 1Department of Pharmacy, Quaid-i-Azam University, Islamabad, 45320, Pakistan; 2Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin ...
Kalam MN +5 more
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PBPK Parameter Set REFSIM. [PDF]
, 2016 PBPK Parameter Set REFSIM.
Alin Cosmanescu (3124272) +7 more
core +1 more source
Pharmaceutics, 2019 The physiologically based pharmacokinetic (PBPK) approach facilitates the construction of novel drug−disease models by allowing incorporation of relevant pathophysiological changes.
Muhammad F. Rasool +7 more
doaj +1 more source
Physiologically Based Pharmacokinetic (PBPK) Models for Ethanol [PDF]
IEEE Transactions on Biomedical Engineering, 2008 Physiologically based pharmacokinetic models have been used to describe the distribution and elimination of ethanol after intravenous administration. These models have been used to estimate the ethanol infusion profile that is sufficient for achieving a prescribed breath ethanol concentration time course in individuals, providing a useful platform for ...
Martin H. Plawecki +4 more
openaire +2 more sources
Model-Informed Precision Dosing of Antibiotics in Osteoarticular Infections
Infection and Drug Resistance, 2022 Lingling Liu,1 Jin Wang,1 Huan Zhang,1 Mengli Chen,2 Yun Cai1 1Center of Medicine Clinical Research, Department of Pharmacy, Medical Supplies Center, PLA General Hospital, Beijing, People’s Republic of China; 2Department of Pharmacy, Medical Supplies ...
Liu L, Wang J, Zhang H, Chen M, Cai Y
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