Results 121 to 130 of about 12,660 (249)
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1223-1234, May 2026.This review evaluates the available pharmacokinetic data on the plasma‐to‐breastmilk transfer of first‐ and second‐line T2DM drugs against available clinical guideline recommendations. A list of drug therapies for treating T2DM was generated from national and international clinical guidelines.
Katherine Richardson +4 more
wiley +1 more source
How to integrate in vitro PK/PD information for toxicity prediction [PDF]
, 2009 Predicting drugs' in vivo effects from in vitro testing requires modelling processes that are not reproduced by in vitro systems. The most obvious difference between the two situations is the absence of the absorption, distribution, metabolism, and ...
Bois, Frédéric Y.
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott +7 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1156-1159, May 2026.ASCPT has a mission to advance clinical pharmacology and translational sciences to reduce health disparities. The development, regulatory, and outcomes (DRO) network within ASCPT strives to advance pharmacoequity globally. Pharmacoequity, coined by Utibe Essien (2021), is the principle that all individuals, regardless of race, ethnicity, geography, or ...
Priya Jayachandran +13 more
wiley +1 more source
Drug Design, Development and TherapyXiaofei Wu, Ziyang Wang, Shupeng Liu, Hongyun Wang Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug ...
Wu X, Wang Z, Liu S, Wang H
doaj
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1195-1204, May 2026.The global HIV response aims for widespread availability of affordable, quality‐assured long‐acting antiretroviral (LA ARV) drugs to achieve sustained epidemic control, particularly in low‐ and middle‐income countries. This report summarizes key discussion points, findings, and outcomes from an international workshop on generic LA ARVs, held in ...
Usman Arshad +22 more
wiley +1 more source
CPT: Pharmacometrics & Systems PharmacologyAdult patients with anaplastic lymphoma kinase positive (ALK+) advanced non–small‐cell lung cancer (NSCLC) are treated with 600 mg alectinib twice daily (BID) as first‐line treatment.
Tamara vanDonge +6 more
doaj +1 more source
Non-equilibrium entangled steady state of two independent two-level systems
, 2011 We determine and study the steady state of two independent two-level systems weakly coupled to a stationary non-equilibrium environment. Whereas this bipartite state is necessarily uncorrelated if the splitting energies of the two-level systems are ...
A. Peres +24 more
core +2 more sources
Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1216-1222, May 2026.Pharmacometrics (PMX) in Africa has transitioned from foundational capacity‐building to job creation, scientific leadership, regulatory influence, and health innovation. To accelerate this progress, the 2025 Pharmacometrics Africa Conference (PMXAC‐2025) convened key stakeholders to consolidate the continental PMX community, review progress in local ...
Babatunde Ayodeji Adeagbo +12 more
wiley +1 more source
Modeling and Simulation of Triclosan Kinetics and Distribution in Humans Using a PBPK Model [PDF]
, 2015 Andreassen, Monica +5 more
core +6 more sources