Results 11 to 20 of about 13,844,580 (194)
Physiologically based pharmacokinetic (PBPK) model of chlorzoxazone
, 2023 This repository provides the chlorzoxazone physiologically based pharmacokinetic (PBPK) model. If you have any questions or problems please open an issue FundingMatthias König were supported by the Federal Ministry of Education and Research (BMBF ...
Küttner, Jonas, König, Matthias
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Pharmaceutics, 2023 Enavogliflozin is a sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor approved for clinical use in South Korea. As SGLT2 inhibitors are a treatment option for patients with diabetes, enavogliflozin is expected to be prescribed in various ...
Min-Soo Kim +11 more
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2022 Physiologically‐based pharmacokinetic (PBPK) models have an important role in drug discovery/development and decision making in regulatory submissions.
Luna Prieto Garcia +5 more
doaj +1 more source
Frontiers in Pharmacology, 2022 This study aimed to apply a physiologically based pharmacokinetic (PBPK) model to predict optimal dosing regimens of pazopanib (PAZ) for safe and effective administration when co-administered with CYP3A4 inhibitors, acid-reducing agents, food, and ...
Chunnuan Wu +16 more
doaj +1 more source
Adapting physiologically-based pharmacokinetic models for machine learning applications
Scientific Reports, 2023 Both machine learning and physiologically-based pharmacokinetic models are becoming essential components of the drug development process. Integrating the predictive capabilities of physiologically-based pharmacokinetic (PBPK) models within machine ...
Sohaib Habiballah, Brad Reisfeld
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Pravastatin physiological based pharmacokinetics model (PBPK)
, 2022 This repository provides the pravastatin physiological based pharmacokinetics model (PBPK). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany ...
König, Matthias, Leal Pujol, Helen
core +1 more source
Omeprazole physiological based pharmacokinetics model (PBPK)
, 2021 This repository provides the omeprazole physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research
Balci, Sükrü, König, Matthias
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Physiologically based pharmacokinetic (PBPK) model of talinolol
, 2023 <p>This repository provides the talinolol physiologically based pharmacokinetic (PBPK) model.</p> <p>If you have any questions or problems please <a href="https://github.com/matthiaskoenig/talinolol-model/issues">open an issue</
Stemmer Mallol, Beatrice Amelie +1 more
core +2 more sources
Omeprazole physiological based pharmacokinetics model (PBPK)
, 2022 This repository provides the pravastatin physiological based pharmacokinetics model (PBPK). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany ...
König, Matthias, Leal Pujol, Helen
core +1 more source