Results 21 to 30 of about 8,529 (239)
Adapting physiologically-based pharmacokinetic models for machine learning applications
Scientific Reports, 2023 Both machine learning and physiologically-based pharmacokinetic models are becoming essential components of the drug development process. Integrating the predictive capabilities of physiologically-based pharmacokinetic (PBPK) models within machine ...
Sohaib Habiballah, Brad Reisfeld
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Pravastatin physiological based pharmacokinetics model (PBPK)
, 2022 This repository provides the pravastatin physiological based pharmacokinetics model (PBPK). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany ...
König, Matthias, Leal Pujol, Helen
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Physiologically based pharmacokinetic (PBPK) model of talinolol
, 2023 <p>This repository provides the talinolol physiologically based pharmacokinetic (PBPK) model.</p> <p>If you have any questions or problems please <a href="https://github.com/matthiaskoenig/talinolol-model/issues">open an issue</
Stemmer Mallol, Beatrice Amelie +1 more
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Omeprazole physiological based pharmacokinetics model (PBPK)
, 2021 This repository provides the omeprazole physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research
Balci, Sükrü, König, Matthias
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Modelling and PBPK Simulation in Drug Discovery [PDF]
The AAPS Journal, 2009 Physiologically based pharmacokinetic (PBPK) models are composed of a series of differential equations and have been implemented in a number of commercial software packages. These models require species-specific and compound-specific input parameters and allow for the prediction of plasma and tissue concentration time profiles after intravenous and ...
Hannah M, Jones +2 more
openaire +2 more sources
Omeprazole physiological based pharmacokinetics model (PBPK)
, 2022 This repository provides the pravastatin physiological based pharmacokinetics model (PBPK). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany ...
König, Matthias, Leal Pujol, Helen
core +1 more source
Simvastatin and cholesterol physiological based pharmacokinetics model (PBPK)
, 2023 This repository provides the simvastatin and cholesterol physiological based pharmacokinetics model (PBPK). If you have any questions or problems please open an issue FundingFlorian Bartsch and Matthias König is supported by the Federal Ministry of ...
König, Matthias, Bartsch, Florian
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CPT: Pharmacometrics & Systems Pharmacology, 2022 There has been a significant increase in the use of physiologically based pharmacokinetic (PBPK) models during the past 20 years, especially for pediatrics.
Trevor N. Johnson +2 more
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Physiologically Based Pharmacokinetic (PBPK) Models for Ethanol [PDF]
IEEE Transactions on Biomedical Engineering, 2008 Physiologically based pharmacokinetic models have been used to describe the distribution and elimination of ethanol after intravenous administration. These models have been used to estimate the ethanol infusion profile that is sufficient for achieving a prescribed breath ethanol concentration time course in individuals, providing a useful platform for ...
Martin H. Plawecki +4 more
openaire +2 more sources
Metoprolol physiological based pharmacokinetics model (PBPK)
, 2021 This repository provides the metoprolol physiological based pharmacokinetics/pharmacodynamics model (PBPK/PD). If you have any questions or problems please open an issue FundingMatthias König is supported by the Federal Ministry of Education and Research
König, Matthias, Ogata, Paula
core +1 more source