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Chlorpyrifos PBPK/PD model for multiple routes of exposure
Xenobiotica, 20141. Chlorpyrifos (CPF) is an important pesticide used to control crop insects. Human Exposures to CPF will occur primarily through oral exposure to residues on foods. A physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model has been developed that describes the relationship between oral, dermal and inhalation doses of CPF and key events ...
Torka S, Poet +3 more
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Probabilistic dose–response modeling: Case study using dichloromethane PBPK model results
Regulatory Toxicology and Pharmacology, 2007A revised assessment of dichloromethane (DCM) has recently been reported that examines the influence of human genetic polymorphisms on cancer risks using deterministic PBPK and dose-response modeling in the mouse combined with probabilistic PBPK modeling in humans.
Dale J, Marino, Thomas B, Starr
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Rapid PBPK modeling with the httk model
2018A Course on Physiologically Based Pharmacokinetic (PBPK) Modeling Given at ScitoVation Nov ...
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International Journal of Environmental Research and Public Health, 2023
Deepika Deepika, Vikas Kumar
exaly
Deepika Deepika, Vikas Kumar
exaly
Sensitivity analysis of PBPK models
Toxicology Letters, 2010G. Loizou, K. Mcnally
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Physiologically Based Pharmacokinetic (PBPK) Modelling
2022Ankit Balhara +2 more
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