Optimisation of Intramuscular Sustained Release-Nano-Formulations Using In Silico Modelling [PDF]
, 2014 Back, D +4 more
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Systematic Engineering Approach to Development and Identification of Physiologically-Based Pharmacokinetic Models [PDF]
, 2011 Gani, Rafiqul +3 more
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Investigations of the effects of different ventilation structures on physiologically based pharmacokinetic modeling (PBPK) simulations [PDF]
, 2016 Yokley, Karen A
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In vivo biodistribution and physiologically based pharmacokinetic modeling of inhaled fresh and aged cerium oxide nanoparticles in rats [PDF]
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Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example [PDF]
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The AAPS Journal, 2016With the great interests in the discovery and development of drug products containing nanoparticles, there is a great demand of quantitative tools for assessing quality, safety, and efficacy of these products. Physiologically based pharmacokinetic (PBPK) modeling and simulation approaches provide excellent tools for describing and predicting in vivo ...
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Postnatal Growth Considerations for PBPK Modeling
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