Results 171 to 180 of about 12,660 (249)

Tissue Distribution and Pharmacokinetic Characteristics of Aztreonam Based on Multi-Species PBPK Model. [PDF]

Pharmaceutics
Ye X, Sun X, Zhang J, Yu M, Wen N, Geng X, Liu Y.   +6 more
europepmc   +1 more source

Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model. [PDF]

Pharmaceutics, 2022
Shuklinova O, Dorożyński P, Kulinowski P, Polak S.   +3 more
europepmc   +1 more source

Editorial: Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches

Frontiers in Pediatrics, 2022
André Dallmann, John N. van den Anker, John N. van den Anker   +2 more
openaire   +3 more sources

Specific quantification of intact lipid nanocapsules in rats using FRET: biodistribution and PBPK model development. [PDF]

Nanomedicine (Lond)
Elfatairi R, Ou J, Lebreton V, Mahdjoub M, Kaeokhamloed N, Bejaud J, Hilairet G, Gattacceca F, Roger E, Legeay S.   +9 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug-Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors. [PDF]

J Clin Pharmacol
Choules MP, Otsuka Y, Nielsen JC, Iwai M, Bonate PL.   +4 more
europepmc   +1 more source

Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases. [PDF]

J Pharmacokinet Pharmacodyn, 2021
Bloomingdale P, Bakshi S, Maass C, van Maanen E, Pichardo-Almarza C, Yadav DB, van der Graaf P, Mehrotra N.   +7 more
europepmc   +1 more source

Development of a PBPK model of psilocybin/psilocin from Psilocybe cubensis (magic mushroom) in mice, rats, and humans. [PDF]

Sci Rep
Thaoboonruang N, Lohitnavy O, Ya K, Lohitnavy M.   +3 more
europepmc   +1 more source

Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels [PDF]

, 2017
Georg Hempel, Kristin J. R. Dickschen, Michael Block, Stefan Willmann   +3 more
core   +1 more source

Genotype, Ethnicity, and Drug-Drug Interaction Modeling as Means of Verifying Transporter Biomarker PBPK Model: The Coproporphyrin-I Story. [PDF]

CPT Pharmacometrics Syst Pharmacol
Ujihira Y, Tan SPF, Scotcher D, Galetin A.   +3 more
europepmc   +1 more source

Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study. [PDF]

J Pharmacokinet Pharmacodyn, 2021
Le Merdy M, Mullin J, Lukacova V.
europepmc   +1 more source