Results 181 to 190 of about 13,844,580 (194)

The Role of “Physiologically Based Pharmacokinetic Model (PBPK)” New Approach Methodology (NAM) in Pharmaceuticals and Environmental Chemical Risk Assessment

International Journal of Environmental Research and Public Health, 2023
Deepika Deepika, Vikas Kumar
exaly  

Quantitative analysis of an impact of P-glycoprotein on edoxaban's disposition using a human physiologically based pharmacokinetic (PBPK) model

International Journal of Pharmaceutics, 2021
Tsuyoshi Mikkaichi, Yasushi Yoshigae, Noriko Okudaira   +2 more
exaly  

Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends

Frontiers in Pharmacology, 2021
Caroline Samer, Youssef Daali, Yvonne Gloor   +2 more
exaly  

Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE)

Toxicology Letters, 1993
J M Gearhart, J W Fisher, H J Clewell
exaly  

Monoclonal antibody disposition: a simplified PBPK model and its implications for the derivation and interpretation of classical compartment models

Journal of Pharmacokinetics and Pharmacodynamics, 2014
Wilhelm Huisinga
exaly  

A translational platform PBPK model for antibody disposition in the brain

Journal of Pharmacokinetics and Pharmacodynamics, 2019
Dhaval K Shah, Hsueh-Yuan Chang, Shengjia Wu   +2 more
exaly  

Mechanistic prediction of food effects for Compound A tablet using PBPK model

Saudi Journal of Biological Sciences, 2017
Aidong Wen, Lei Shi, Lin Yang
exaly  

A Bayesian population PBPK model for multiroute chloroform exposure

Journal of Exposure Science and Environmental Epidemiology, 2009
Panos G. Georgopoulos
exaly  

Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach

Toxicology and Applied Pharmacology, 2009
Weihsueh A Chiu, Marina V Evans
exaly  

Chlorpyrifos PBPK/PD model for multiple routes of exposure

Xenobiotica, 2014
Torka S Poet, Charles Timchalk, Michael J Bartels   +2 more
exaly