Results 161 to 170 of about 13,844,580 (194)

Using a PBPK Model Incorporating Lymphatic Absorption to Predict Food Effect, Multiple Dosing, and Hepatic Impairment of Cannabidiol. [PDF]

Clin Transl Sci
Qian L, Zhou Z.
europepmc   +1 more source

Issue Information

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.
wiley   +1 more source

Tissue Distribution and Pharmacokinetic Characteristics of Aztreonam Based on Multi-Species PBPK Model. [PDF]

Pharmaceutics
Ye X, Sun X, Zhang J, Yu M, Wen N, Geng X, Liu Y.   +6 more
europepmc   +1 more source

Quality Control Dissolution Data Is Biopredictive for a Modified Release Ropinirole Formulation: Virtual Experiment with the Use of Re-Developed and Verified PBPK Model. [PDF]

Pharmaceutics, 2022
Shuklinova O, Dorożyński P, Kulinowski P, Polak S.   +3 more
europepmc   +1 more source

Specific quantification of intact lipid nanocapsules in rats using FRET: biodistribution and PBPK model development. [PDF]

Nanomedicine (Lond)
Elfatairi R, Ou J, Lebreton V, Mahdjoub M, Kaeokhamloed N, Bejaud J, Hilairet G, Gattacceca F, Roger E, Legeay S.   +9 more
europepmc   +1 more source

Minimal brain PBPK model to support the preclinical and clinical development of antibody therapeutics for CNS diseases. [PDF]

J Pharmacokinet Pharmacodyn, 2021
Bloomingdale P, Bakshi S, Maass C, van Maanen E, Pichardo-Almarza C, Yadav DB, van der Graaf P, Mehrotra N.   +7 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug-Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors. [PDF]

J Clin Pharmacol
Choules MP, Otsuka Y, Nielsen JC, Iwai M, Bonate PL.   +4 more
europepmc   +1 more source

Development of a PBPK model of psilocybin/psilocin from Psilocybe cubensis (magic mushroom) in mice, rats, and humans. [PDF]

Sci Rep
Thaoboonruang N, Lohitnavy O, Ya K, Lohitnavy M.   +3 more
europepmc   +1 more source

Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using <i>in silico</i>, <i>in vitro</i> and human biomonitoring data. [PDF]

Front Pharmacol, 2023
McNally K, Sams C, Hogg A, Loizou G.
europepmc   +1 more source

Genotype, Ethnicity, and Drug-Drug Interaction Modeling as Means of Verifying Transporter Biomarker PBPK Model: The Coproporphyrin-I Story. [PDF]

CPT Pharmacometrics Syst Pharmacol
Ujihira Y, Tan SPF, Scotcher D, Galetin A.   +3 more
europepmc   +1 more source