Results 211 to 220 of about 4,447,834 (239)
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Gangliosides enhance neurite outgrowth in PC12 cells
Developmental Brain Research, 1983Gangliosides are surface membrane components that have been suggested to play a significant role in the regulation of many cellular events including neuronal differentiation, growth and regeneration. We have chosen PC12 cell as a model system to study the influence of exogenously added glycosphyngolipids on in vitro differentiation and regeneration.
G. Ferrari, M. Fabris, A. Gorio
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1998
Brains from patients with Alzheimer’s disease are characterized by extracellular depositions of β-amyloid peptide (Aβ) and an intracellular accumulation of paired helical filaments (PHF) consisting of hyperphosphorylated tau proteins. The normal phosphorylation of tau protein controls microtubule polymerisation and stabilization, whereas its abnormal ...
Fjord-Larsen, Lone +2 more
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Brains from patients with Alzheimer’s disease are characterized by extracellular depositions of β-amyloid peptide (Aβ) and an intracellular accumulation of paired helical filaments (PHF) consisting of hyperphosphorylated tau proteins. The normal phosphorylation of tau protein controls microtubule polymerisation and stabilization, whereas its abnormal ...
Fjord-Larsen, Lone +2 more
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EXPRESSION OF P2X PURINOCEPTORS IN PC12 PHAEOCHROMOCYTOMA CELLS
Clinical and Experimental Pharmacology and Physiology, 2007SUMMARY The PC12 cell line, which was cloned from a rat adrenal phaeochromocytoma, is a useful model system. It expresses neuronal properties after treatment with nerve growth factor (NGF). The nervous system‐specific P2X receptor subtype P2X2 was initially cloned from PC12 cells, but little is known about the expression of other subtypes of P2X ...
Ji-Hu, Sun +2 more
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Cyclosporine A- and FK506-induced apoptosis in PC12 cells
Cell Biology and Toxicology, 2007The purpose of this study was to examine, using glycogen synthase kinase (GSK) inhibitors, whether GSK-3 is involved in cyclosporine A (CsA)- and FK506-induced apoptosis in PC12 cells. CsA and FK506 increased apoptotic cell death with morphological changes characterized by cell shrinkage and nuclear condensation or fragmentation.
T, Takadera +3 more
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Cytotoxic effect of sodium nitroprusside on PC12 cells
Chemosphere, 1997To investigate the biochemical mechanism responsible for NO-induced neurotoxicity, the effect of sodium nitroprusside(SNP), a NO-generating agent, on PC12 cells was studied. The cell density was dose-dependently inhibited by SNP. Neuronally differentiated PC12 cells showed a higher resistance to SNP than the undifferentiated cells.
Y, Nakamura +4 more
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Diverse Effect of Tributyltin on Apoptosis in PC12 Cells
Biochemical and Biophysical Research Communications, 2000It has not been fully elucidated how endocrine-disrupting chemicals disrupt hormone functions or how strong their effects are compared with natural hormones. There is little information concerning the effects of tributyltin (TBT), one of the endocrine disrupters on living organisms.
O, Yamanoshita +8 more
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Regulation of Creb by Moderate Hypoxia in PC12 Cells
2002The mechanisms by which excitable cells adapt and respond to changes in O2 levels remain largely unknown. We have investigated the effect of hypoxia on the cyclic AMP response element binding protein (CREB) transcription factor. PC12 cells were exposed to moderate levels of hypoxia (5% O2) for various times between 20 min and 6 hr.
D, Beitner-Johnson +3 more
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Effects of erythropoietin on pc12 cells
Neuroscience Research, 1997K KOSHIMURA +3 more
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Wnt-1 dependent activation of the survival factor NF-?B in PC12 cells
Journal of Neuroscience Research, 2000A P Soler
exaly