Results 81 to 90 of about 4,447,834 (239)

Cell viability of pheochromocytoma 12 (PC12) and differentiated PC12 cells following 24 hours ketamine treatment.

, 2013
A) Phase contrast image of undifferentiated PC12 cells. B) Phase contrast image of PC12 cells differentiated with nerve growth factor (NGF) (50 ng/ml) for 6 days. C) Dosage effects of ketamine on cell viability in undifferentiated PC12 cells.
Wan-Hua Amy Yu (310506), Wai Ping Lam (310502), Sijie Tan (310500), David T. Yew (310508), Maria S. M. Wai (310503)   +4 more
core   +1 more source

Chinese Angelica Polysaccharide (CAP) Alleviates LPS-Induced Inflammation and Apoptosis by Down-Regulating COX-1 in PC12 Cells

Cellular Physiology and Biochemistry, 2018
Background/Aims: Chinese angelica polysaccharide (CAP) is the main effective ingredient of angelica sinensis and exerts anti-inflammatory and anti-apoptotic effects on many diseases.
Yunjie Xie, Haitao Zhang, Yang Zhang, Chong Wang, Deyi Duan, Zheng Wang   +5 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Dosage effects of ketamine on dopamine in pheochromocytoma 12 (PC12) cells and differentiated PC12 cells (d-PC12).

, 2013
PC12 cells and d-PC12 cells were exposed to ketamine from 10 to 500 µg/ml for 24 hours. After the treatment, dopamine concentrations were measured using ELISA.
Wan-Hua Amy Yu (310506), Wai Ping Lam (310502), Sijie Tan (310500), David T. Yew (310508), Maria S. M. Wai (310503)   +4 more
core   +1 more source

The Effect of Protein-Rich Extract from Bombyx Batryticatus against Glutamate-Damaged PC12 Cells Via Regulating γ-Aminobutyric Acid Signaling Pathway

Molecules, 2020
Bombyx Batryticatus (BB) is a known traditional Chinese medicine (TCM) utilized to treat convulsions, epilepsy, cough, asthma, headaches, etc. in China for thousands of years.
Li-Ying He, Mei-Bian Hu, Ruo-Lan Li, Rong Zhao, Lin-Hong Fan, Li Wang, Wei Peng, Yu-Jie Liu, Chun-Jie Wu   +8 more
doaj   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Immunofluorescence staining of MAP2 in PC12 cells and colocalization of Cx36 and CaMKII in PC12 cells.

, 2018
(A) PC12 cells exhibited neuron-like characteristics. MAP2-positive staining was in red, and the nuclei were stained with DAPI in blue. (B) Colocalization of Cx36 and CaMKII in PC12 cells.
Yunfei Ma (1777753), Xiaoxi Liu (292827), Deping Han (302417), Jiao Li (261359), Jianqin Xu (833917), Shuang Zhang (117657)   +5 more
core   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger, G., Manfred Gratzl, Gratzl, Manfred, Gudrun Ahnert‐Hilger   +3 more
core   +1 more source