Results 31 to 40 of about 3,963,364 (363)

Molecular Epidemiology of SARS-CoV-2 Omicron Sub-Lineages Isolated from Turkish Patients Infected with COVID-19

open access: yesViruses, 2023
Early detection and characterization of new variants and their impacts enable improved genomic surveillance. This study aims to evaluate the subvariant distribution of Omicron strains isolated from Turkish cases to determine the rate of antiviral ...
Murat Sayan, Ayse Arikan, Erdal Sanlidag
doaj   +1 more source

The development of a 16S rRNA gene based PCR for the identification of Streptococcus pneumoniae and comparison with four other species specific PCR assays [PDF]

open access: yes, 2010
Background: Streptococcus pneumoniae is one of the most frequently encountered pathogens in humans but its differentiation from closely related but less pathogenic streptococci remains a challenge.
Nabil Abdullah El Aila   +30 more
core   +3 more sources

³¹P Saturation Transfer and Phosphocreatine Imaging in the Monkey Brain [PDF]

open access: yes, 1991
³¹P magnetic resonance imaging with chemical-shift discrimination by selective excitation has been employed to determine the phosphocreatine (PCr) distribution in the brains of three juvenile macaque monkeys.
Allman, John   +4 more
core   +1 more source

Applying multi-criteria optimisation to develop cognitive models [PDF]

open access: yes, 2005
A scientific theory is developed by modelling empirical data in a range of domains. The goal of developing a theory is to optimise the fit of the theory to as many experimental settings as possible, whilst retaining some qualitative properties such as ...
Gobet, F, Lane, PCR
core  

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Simple environments fail as illustrations of intelligence: A review of R. Pfeifer and C. Scheier [PDF]

open access: yes, 2001
The field of cognitive science has always supported a variety of modes of research, often polarised into those seeking high-level explanations of intelligence and those seeking low-level, perhaps even neuro-physiological, explanations.
Gobet, F, Lane, PCR
core  

Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care [PDF]

open access: yes, 2015
Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 ...
Bonczkowski, Pawel   +18 more
core   +9 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Extraction of HCV-RNA from Plasma Samples: Development towards Semiautomation

open access: yesInternational Journal of Analytical Chemistry, 2015
A semiautomated extraction protocol of HCV-RNA using Favorgen RNA extraction kit has been developed. The kit provided protocol was modified by replacing manual spin steps with vacuum filtration. The assay performance was evaluated by real-time qPCR based
Imran Amin   +3 more
doaj   +1 more source

EPAM/CHREST tutorial: Fifty years of simulating human learning [PDF]

open access: yes, 2009
Generating quantitative predictions for complex cognitive phenomena requires precise implementations of the underlying cognitive theory. This tutorial focuses on the EPAM/CHREST tradition, which has been providing significant models of human ...
Gobet, F, Lane, PCR
core  

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