Results 51 to 60 of about 2,958,232 (316)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Development of real-time PCR for detection of Mycoplasma hominis [PDF]

open access: yes, 2004
Background: Mycoplasma hominis is associated with pelvic inflammatory disease, bacterial vaginosis, post partum fever, sepsis and infections of the central nervous system often leading to serious conditions.
Christiansen, G   +19 more
core   +1 more source

Early detection of nosocomial pathogens in air and surfaces using an innovative genetic approach for surveillance in healthcare settings

open access: yesAntimicrobial Resistance and Infection Control
Background Healthcare-associated infections remain a major cause of morbidity, mortality, and financial burden worldwide, further exacerbated by the emergence of antimicrobial resistance. Environmental reservoirs of pathogens, including air and surfaces,
Antonio Martínez-Murcia   +6 more
doaj   +1 more source

Identification of Listeria Isolates by Using a Pragmatic Multilocus Phylogenetic Analysis

open access: yesMicrobiology Research
Species identification of Listeria isolates remained a tedious process still based on culturing methods that, in recent years, have led to the description of many species that are not even part of the genus Listeria.
Antonio Martínez-Murcia   +2 more
doaj   +1 more source

Penerapan Metode UCD (User Centered Design) Pada E-Commerce Putri Intan Shop Berbasis Web

open access: yesJurnal Teknologi dan Sistem Informasi, 2017
Pertumbuhan pesat pangsa pasar e-commerce di Indonesia memang sudah tidak bisa diragukan lagi. Dengan jumlah pengguna internet yang mencapai angka 82 juta orang atau sekitar 30% dari total penduduk di Indonesia, pasar e-commerce menjadi tambang emas yang
Intan Sandra Yatana Saputri   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

MOLECULAR ANALYSIS OF FIELD INFECTIOUS BURSAL DISEASE VIRUS ISOLATED IN SULAIMANI/IRAQ [PDF]

open access: yesAssiut Veterinary Medical Journal
Infectious Bursal Disease (IBD) is also known as Gumboro disease, where the illness was initially identified. It is an extremely transmissible immune suppressor virus that has a significant financial impact on the poultry sector around the world ...
MOHAMMED BABASHEIKH   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Micro Circulating Pcr Chip Using a Suction-Type Membrane for Fluidic Transport

open access: yes, 2010
A new micromachined circulating polymerase chain reaction ( PCR) chip is reported in this study. A novel liquid transportation mechanism utilizing a suction-type membrane and three microvalves were used to create a new microfluidic control module to ...
陳炳煇;陳培哲   +1 more
core   +1 more source

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