Results 61 to 70 of about 3,963,364 (363)
An investigation into the effect of ageing on expert memory with CHREST [PDF]
, 2007 CHREST is a cognitive architecture that models human perception, learning, memory, and problem solving, and which has successfully simulated numerous human experimental data on chess. In this paper, we describe an investigation into the effects of ageing
Gobet, F, Lane, PCR, Smith, RL
core
A computational method for estimating the PCR duplication rate in DNA and RNA-seq experiments. [PDF]
, 2017 BackgroundPCR amplification is an important step in the preparation of DNA sequencing libraries prior to high-throughput sequencing. PCR amplification introduces redundant reads in the sequence data and estimating the PCR duplication rate is important to
Bansal, Vikas
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BioMedica, 2020 Coronavirus disease-2019 (COVID-19) outbreak was first declared as emergency on January 30th2020 by World Health Organization (WHO). The Government of Pakistan presented a National action plan, which aimed to inhibit the spread of this Corona virus and ...
Ghazala Rubi, Irfan Malik, Zainab Javaid
doaj +1 more source
Combining low-level perception with expectations in CHREST [PDF]
, 2003 The ability of humans to reliably perceive and recognise objects relies on an interaction between information seen in the visual image and prior expectations.
Gobet, F, Lane, PCR, Sykes, A
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Transgendered in Alaska: Navigating the Changing Legal Landscape for Change in Gender Petitions [PDF]
, 2009 Background: Detecting intracellular bacterial symbionts can be challenging when they persist at very low densities. Wolbachia, a widespread bacterial endosymbiont of invertebrates, is particularly challenging.
Klasson, Lisa +3 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Checking chess checks with chunks: A model of simple check detection [PDF]
, 2009 The procedure by which humans identify checks in check positions is not well understood. We report here our experience in modelling this process with CHREST, a general-purpose cognitive model that has previously successfully captured a variety of ...
Gobet, F, Lane, PCR, Smith, RL
core
Enhanced analysis of real-time PCR data by using a variable efficiency model : FPK-PCR [PDF]
, 2011 Current methodology in real-time Polymerase chain reaction (PCR) analysis performs well provided PCR efficiency remains constant over reactions. Yet, small changes in efficiency can lead to large quantification errors. Particularly in biological samples,
Goetghebeur, Els +3 more
core +3 more sources