Results 81 to 90 of about 3,963,364 (363)

A distributed framework for semi-automatically developing architectures of brain and mind [PDF]

, 2005
Developing comprehensive theories of low-level neuronal brain processes and high-level cognitive behaviours, as well as integrating them, is an ambitious challenge that requires new conceptual, computational, and empirical tools.
Gobet, F, Lane, PCR
core  

Optimizing a PCR protocol for cpn60-based microbiome profiling of samples variously contaminated with host genomic DNA. [PDF]

, 2015
The current recommended protocol for chaperonin-60 (cpn60) universal target based microbiome profiling includes universal PCR of microbiome samples across an annealing temperature gradient to maximize the diversity of sequences amplified.
Chaban, B, Harding, JC, Hill, JE, Johnson, LA   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

CHREST+: A simulation of how humans learn to solve problems using diagrams. [PDF]

, 2000
This paper describes the underlying principles of a computer model, CHREST+, which learns to solve problems using diagrammatic representations. Although earlier work has determined that experts store domain-specific information within schemata, no ...
Cheng, PCH, Gobet, F, Lane, PCR
core  

Comparison of droplet digital PCR and qPCR for the quantification of Shiga toxin-producing Escherichia coli in bovine feces [PDF]

, 2016
Cattle are considered to be the main reservoir for Shiga toxin-producing Escherichia coli (STEC) and are often the direct or indirect source of STEC outbreaks in humans.
De Reu, Koen, De Zutter, Lieven, Heyndrickx, Marc, Van Coillie, Els, Verhaegen, Bavo, Verstraete, Karen   +5 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Reassessment of Aeromonas oralensis. Comment on Mashzhan et al. Whole-Genome Sequencing of a Potentially Novel Aeromonas Species Isolated from Diseased Siberian Sturgeon (Acipenser baerii) Using Oxford Nanopore Sequencing. Microorganisms 2025, 13, 1680

Microorganisms
In this comment, we re-evaluate the proposal of Aeromonas oralensis as a novel species by Mashzhan et al. (2025) [...]
Antonio Martínez-Murcia, Aaron Navarro, Caridad Miró-Pina   +2 more
doaj   +1 more source

PCR Based Genotyping of Lulu Cattle of Nepal for A1, A2 Type Beta-caseins [PDF]

, 2020
Lulu is an indigenous breed of cattle (Bos taurus) found in high altitude regions of western Nepal. Population of Lulu cattle has been declining due to introgression with other exotic breeds to increase milk productivity.
Budhathoki, N. (Nabina), GC, S. (Sudarshan), Gorkhali, N. A. (Neena), Lama, S. (Srijana), Pokharel, P. (Prashanna), Pokhrel, B. R. (Bhoj), Sapkota, S. (Saroj), Sherpa, C. (Chhiring)   +7 more
core  

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer [PDF]

, 2013
Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
A Goldhirsch, A Hurtado, A Noske, AA Lazar, AC Wolff, Andre Robidoux, BM Müller, Bruno V Sinn, C Denkert, Carsten Denkert, Christine Solbach, CK Osborne, D Slamon, DG Altman, DJ Dabbs, EA Perez, EH Romond, FL Baehner, G Hennig, G Konecny, G Pentheroudakis, G von Minckwitz, G von Minckwitz, G von Minckwitz, Gunter von Minckwitz, H Joensuu, Hans Tesch, I Pinhel, J Baselga, J Baselga, Jan C Brase, Jens Huober, Judith Prinzler, K Bohmann, Keyur Mehta, Knut Engels, L Gianni, L Gianni, LM McShane, M Bonetti, M Dowsett, M Dowsett, M Filipits, M Untch, M Untch, M Untch, M Untch, Martin-Leo Hansmann, Mattea Reinisch, ME Hammond, Michael Untch, MJ Piccart-Gebhart, MP Fereshteh, PC Roche, Peter A Fasching, Ralf Kronenwett, S Johnston, S Paik, S Paik, Sibylle Loibl, Silvia Darb-Esfahani, T Lahusen, W Zhao   +62 more
core   +1 more source

HIV Viral Load PCR Measurement [PDF]

, 2020
National Cancer Institute
openalex   +1 more source