Results 41 to 50 of about 3,764,452 (295)

EPAM/CHREST tutorial: Fifty years of simulating human learning [PDF]

open access: yes, 2009
Generating quantitative predictions for complex cognitive phenomena requires precise implementations of the underlying cognitive theory. This tutorial focuses on the EPAM/CHREST tradition, which has been providing significant models of human ...
Gobet, F, Lane, PCR
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Penerapan Metode UCD (User Centered Design) Pada E-Commerce Putri Intan Shop Berbasis Web

open access: yesJurnal Teknologi dan Sistem Informasi, 2017
Pertumbuhan pesat pangsa pasar e-commerce di Indonesia memang sudah tidak bisa diragukan lagi. Dengan jumlah pengguna internet yang mencapai angka 82 juta orang atau sekitar 30% dari total penduduk di Indonesia, pasar e-commerce menjadi tambang emas yang
Intan Sandra Yatana Saputri   +2 more
doaj   +1 more source

Computational models of the development of perceptual expertise [PDF]

open access: yes, 2007
In a recent article, Palmeri, Wong and Gauthier have argued that computational models may help direct hypotheses about the development of perceptual expertise.
Campitelli, G, Gobet, F, Lane, PCR
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Towards a model of expectation-driven perception [PDF]

open access: yes, 2003
Human perception is an active process by which meaningful information is gathered from the external environment. Application areas such as human-computer interaction (HCI), or the role of human experts in image analysis, highlight the need to ...
Gobet, F, Lane, PCR
core  

Digital PCR as a tool to measure HIV persistence [PDF]

open access: yes, 2018
Although antiretroviral therapy is able to suppress HIV replication in infected patients, the virus persists and rebounds when treatment is stopped.
Bosman, Kobus   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Identification of Listeria Isolates by Using a Pragmatic Multilocus Phylogenetic Analysis

open access: yesMicrobiology Research
Species identification of Listeria isolates remained a tedious process still based on culturing methods that, in recent years, have led to the description of many species that are not even part of the genus Listeria.
Antonio Martínez-Murcia   +2 more
doaj   +1 more source

An investigation into the effect of ageing on expert memory with CHREST [PDF]

open access: yes, 2007
CHREST is a cognitive architecture that models human perception, learning, memory, and problem solving, and which has successfully simulated numerous human experimental data on chess. In this paper, we describe an investigation into the effects of ageing
Gobet, F, Lane, PCR, Smith, RL
core  

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