Results 301 to 310 of about 264,642 (338)

Is Laparoscopic/Robotic Total Gastrectomy a Reasonable and Adequate Treatment for Proximal Advanced Gastric Cancer?

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Although the level of evidence is not high, this review indicates that laparoscopic total gastrectomy for advanced gastric cancer can be safely performed with the progress of surgical techniques, and there is little risk of worsening survival outcomes.
Takahiro Kinoshita   +3 more
wiley   +1 more source

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa   +5 more
wiley   +1 more source

<sup>18</sup>F-BMS-986229 PET imaging of tumor PD-L1 expression in glioblastoma patients. [PDF]

open access: yesEJNMMI Res
Grkovski M   +7 more
europepmc   +1 more source

Unexpectedly High Incidence of Immune‐Related Adverse Events in Gastric Cancer Patients Who Received Conversion Surgery After Nivolumab‐Including Chemotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Nivolumab‐including chemotherapy (nivo‐CTX) for stage IV gastric cancer (GC) may increase the chance of conversion surgery but risk of immune‐related adverse events (irAEs) during perioperative period remains unclear. Methods We examined irAEs in 36 patients with marginally resectable GC who received nivo‐CTX followed by surgery ...
Masashi Nishino   +11 more
wiley   +1 more source

The JAK2 46/1 haplotype influences PD-L1 expression.

open access: yesBlood
Carreño-Tarragona G   +12 more
europepmc   +1 more source

Conversion Therapy for cT4b and M1 Esophageal Squamous Cell Carcinoma: A Comprehensive Systematic Review

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
We systematically reviewed conversion therapy for esophageal squamous cell carcinoma and propose a response‐based treatment strategy for cT4b and M1 disease. For cT4b, we emphasize definitive chemoradiotherapy with timed re‐evaluation and selective salvage or chemoselection to surgery; for M1, conversion is reserved for limited‐burden responders with ...
Eisuke Booka, Hiroya Takeuchi
wiley   +1 more source

Extracellular Vesicles and PD-L1-A Review of Complex Immunoregulatory Properties and Clinical Importance. [PDF]

open access: yesBiomedicines
Kiełbowski K   +5 more
europepmc   +1 more source

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