Results 261 to 270 of about 85,787 (336)

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Spatial transcriptomics reveals the mechanistic role of lactate metabolism in the pancreatic ductal adenocarcinoma microenvironment. [PDF]

Front Immunol
Gao F, Tang Z, Lian J, Zhang L.
europepmc   +1 more source

An Updated Narrative Review on the Therapeutic Potential of Resveratrol in the Treatment of Cancer

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongoing research to find suitable and effective sensitizers.
Mohammad Ashraful Islam, Al Amin, Md. Abdul Aziz, Md. Mahabubur Rahaman, Jakir Hossain, Jakir Ahmed Chowdhury, Mohammad Safiqul Islam   +6 more
wiley   +1 more source

Single-cell analysis of anchorage-independent growth ability in pancreatic ductal adenocarcinoma cell lines. [PDF]

BMC Res Notes
Shichi Y, Shinji S, Fujiwara M, Ogawa Y, Yoshimura Y, Nonaka K, Yoshida H, Ishiwata T.   +7 more
europepmc   +1 more source

Extracellular pH and NHE1 Regulate Ductal Branching Morphogenesis in Organotypic Cultures of Human Pancreatic Duct Epithelial Cells

Journal of Cellular Physiology, Volume 241, Issue 3, March 2026.
ABSTRACT Branching morphogenesis is a key process for constructing the tree‐like architecture of multiple organs. The mechanisms regulating pancreatic ductal morphogenesis are still poorly understood, especially in the context of the particular pH dynamics of this organ.
Daria Di Molfetta, Marilena Ardone, Francesca Fracasso, Maria Raffaella Greco, Grazia Tamma, Mariangela Centrone, Maria Barile, Maria Tolomeo, Alessia Nisco, Stephan Joel Reshkin, Rosa Angela Cardone   +10 more
wiley   +1 more source

Improving a Plasma Biomarker Panel for Early Detection of Pancreatic Ductal Adenocarcinoma with Aminopeptidase N (ANPEP) and Polymeric Immunoglobulin Receptor (PIGR). [PDF]

Clin Cancer Res
Krusen BM, Gimotty PA, Donahue G, Till JE, Yin M, Carlson EE, Bamlet WR, Carpenter EL, Majumder S, Oberg AL, Zaret KS.   +10 more
europepmc   +1 more source

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Mechanism of ASIC4 in regulating MHC-I-mediated immune evasion in pancreatic cancer. [PDF]

J Transl Med
An Q, An Z, Bo W, Yan C, Sun N, Ma J, Li J, Wang W.   +7 more
europepmc   +1 more source

Early Cancer Detection: What's Going on and What's Next

MedComm, Volume 7, Issue 3, March 2026.
Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley   +1 more source

Giant Pancreatic Acinar Cell Carcinoma: A Case Report and Review of Molecular Pathogenesis and Emerging Therapies. [PDF]

Cureus
Akiyama R, Kawashita Y, Ochiai M, Tateishi M, Ueda T, Nakamura M, Umeda K, Harada S, Abe S, Haraguchi M, Yamaguchi J, Washida Y, Hachitanda Y.   +12 more
europepmc   +1 more source