Results 121 to 130 of about 8,073 (209)

The Sexual Goals of Metoidioplasty Patients and Their Attitudes Toward Using PDE5 Inhibitors and Intracavernosal Injections as Erectile Aids. [PDF]

Sex Med, 2022
Khorrami A, Kumar S, Bertin E, Wassersug R, O'Dwyer C, Mukherjee S, Witherspoon L, Mankowski P, Genoway K, Kavanagh AG.   +9 more
europepmc   +1 more source

Targeting the SARS-CoV-2 3CL^pro and NO/cGMP/PDE5 pathway in COVID-19: a commentary on PDE5 inhibitors. [PDF]

Future Cardiol, 2021
Shirvaliloo M.
europepmc   +1 more source

Genetically proxied inhibition of Phosphodiesterase-5 and cancer risks: A drug-target Mendelian randomization analysis

Scientific Reports
Observational studies found that phosphodiesterase 5 (PDE5) inhibitors use is linked to both increased and decreased risk of cancer; while the causal relationship remains unclear.
Kefu Tang, Binbin Li, Xi Wu, Meng Wang
doaj   +1 more source

Raf-1 kinase inhibitor protein modulation of the cellular response to chemotherapeutic drugs and PDE5 inhibitors [PDF]

, 2011
RKIP was initially discovered as an endogenous inhibitor of the ERK and NF-κB pathways,and was also shown to prolong the activation of GPCRs via inhibition of the GRK2 protein.
Reid, Anne Marie
core   +1 more source

Design, synthesis and development of PDE5 inhibitors [PDF]

This research project is concerned with the design, synthesis and development of new phosphodiesterase 5 (PDE5) inhibitors with improved selectivities and lower toxicities.
Wang, Guocheng
core  

PDE5 inhibitor protects testes [PDF]

Nature Reviews Urology, 2012
openaire   +1 more source

Tadalafil in the treatment of erectile dysfunction

Therapeutics and Clinical Risk Management, 2008
Robert M Coward, Culley C CarsonDivision of Urologic Surgery, University of North Carolina, Chapel Hill, NC, USAAbstract: The treatment for erectile dysfunction (ED) was revolutionized with the development of phosphodiesterase type 5 (PDE5) inhibitors ...
Robert M Coward, Culley C Carson
doaj  

Repurposing PDE5-Inhibitors: Sildenafil Drives Arteriogenesis via Localized Regenerative Inflammation. [PDF]

Int J Mol Sci
Elbs K, Bobrowski L, Arnholdt C, Kübler M, Götz P, Rohrmoser MR, Merkus D, Lasch M, Deindl E.   +8 more
europepmc   +1 more source

Virtual Screening of Phytochemicals From Medicinal Plants as Promising PDE5 Inhibitors Against Erectile Dysfunction. [PDF]

Food Sci Nutr
Boudou F, Berkane A, Belakredar A, Keziz A, Alsaeedi H, Murray BA, Bechelany M, Barhoum A.   +7 more
europepmc   +1 more source

Cyclic Nucleotide Phosphodiesterase Families as Targets to Treat Pulmonary Arterial Hypertension: Beyond PDE5 Inhibitors? [PDF]

Cells
Wang L, Fischmeister R, Manoury B.
europepmc   +1 more source