Results 191 to 200 of about 8,073 (209)

PDE5 Inhibitors

2015
openaire   +1 more source

Design, synthesis and biological evaluation of pyrazolopyrimidinone based potent and selective PDE5 inhibitors for treatment of erectile dysfunction

Bioorganic Chemistry, 2019
Priya Mahajan, Amit Nargotra, Utpal Nandi   +2 more
exaly  

Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5

Bioorganic and Medicinal Chemistry Letters, 2013
Zhen Wang, Jingshan Shen, Haji Akber Aisa   +2 more
exaly  

Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry, 2018
Obdulia Rabal, Juan A Sánchez-Arias, Mar Cuadrado-Tejedor   +2 more
exaly  

Combining Testosterone and PDE5 Inhibitors in Erectile Dysfunction: Basic Rationale and Clinical Evidences

European Urology, 2006
Emanuela A Greco, Giovanni Spera, Antonio Aversa   +2 more
exaly  

Discovery of furyl/thienyl β-carboline derivatives as potent and selective PDE5 inhibitors with excellent vasorelaxant effect

European Journal of Medicinal Chemistry, 2018
Hongbo Zheng, Bin Sun, Chuanle Cheng
exaly  

Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region

Bioorganic and Medicinal Chemistry Letters, 2011
John K Walker, Brian R Bond
exaly  

A molecular dynamics study on specificity and sensitivity of PDE5 inhibitors to PDE5 and PDE6

Biophysical Journal, 2023
openaire   +1 more source

Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors

Bioorganic and Medicinal Chemistry Letters, 2009
Dafydd R Owen, John K Walker, David G Brown   +2 more
exaly  

Are all PDE5 inhibitors the same?

2018
openaire   +1 more source