Results 61 to 70 of about 6,210 (213)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Progress of collection, conservation and utilization of peach germplasm resources at the National Grape and Peach Germplasm Repository (Zhengzhou) [PDF]

Guoshu xuebao
Peach (Prunus persica L.) ranks among the most economically significant temperate fruit crops globally, with China universally acknowledged as its primary center of origin, domestication, and genetic diversity.
WANG Lirong, WU Jinlong, FANG Weichao, ZHU Gengrui, CAO Ke, WANG Xinwei, LI Yong, CHEN Changwen, XIE Jingmei, LI Fangfei, FAN Jiaqi   +10 more
doaj   +1 more source

EcoPêche 2: conceive and evaluate innovative peach orchard management systems to reduce dependance on phytosanitary products

, 2022
Meeting: 10th International Peach SymposiumLocation: Naoussa, GREECEDate: 30/05-03/06/2022International audienceEcoPêche 2 (2019-2023) project is financed by the OFB (French Biodiversity Agency) within the framework of the ECOPHYTO Plan and the DEPHY ...
Borg, Julie, Gallia, Valérie, Mouiren, Christophe, Ruesch, Julien, Codini, Myriam, Plénet, Daniel, Blanc, Philippe, Hostalnou, Eric, Guiraud, Maelle, Labeyrie, Baptiste, Drusch, Stéphanie, Montrognon, Yannick   +11 more
core   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Diversity and Virulence of Diaporthe Species Associated with Peach Trunk Diseases in China

Plants
Peach (Prunus persica L.) is one of the most important and oldest stone fruits grown in China. Though Diaporthe species have more commonly been reported as plant pathogens, endophytes and saprophytes with a wide range of plant hosts, little is known ...
Ying Zhou, Wei Zhang, Pranami D. Abeywickrama, Zhizheng He, Zhixiang Zhang, Yonghua Li, Shifang Li, Zaifeng Fan, Jiye Yan   +8 more
doaj   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan, Karen Hon, Ruby E. Dawson, Teresa Weng, Jelena Solujic, Yu C. J. Chey, James D. Zuiani, Griffith B. Perkins, P. Toby Coates, Chris Drogemuller, Eddie Sanderlin, Lulu Huang, John Finnie, Stefan Rose‐John, Arash Badiei, Phan Nguyen, Brendan J. Jenkins, Mohamed I. Saad   +17 more
wiley   +1 more source

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes, Florian Buehning, Tobias Lerchner, Julia Vogel, Raluca I. Mincu, Matthias Totzeck, Tienush Rassaf, Lars Michel   +7 more
wiley   +1 more source

Insights into the Interaction between the Biocontrol Agent Bacillus amyloliquefaciens QST 713, the Pathogen Monilinia fructicola and Peach Fruit

Agronomy
Brown rot disease caused by Monilinia fructicola is one of the most important peach fruit threats in the world. The use of biological control agents (BCAs), instead of synthetic fungicides, to successfully inhibit postharvest disease development is a ...
Polina C. Tsalgatidou, Anastasia Papageorgiou, Anastasia Boutsika, Michael Chatzidimopoulos, Costas Delis, Dimitrios I. Tsitsigiannis, Epaminondas Paplomatas, Antonios Zambounis   +7 more
doaj   +1 more source