Results 101 to 110 of about 495,930 (304)
Higher-Order Energy Expansions and Spike Locations
, 2004 We consider the following singularly perturbed semilinear elliptic problem: (I)\left\{ \begin{array}{l} \epsilon^{2} \Delta u - u + f(u)=0 \ \ \mbox{in} \ \Omega, \\ u>0 \ \ \mbox{in} \ \ \Omega \ \ \mbox{and} \ \frac{\partial u}{\partial \nu}
Winter, M, Wei, J
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
On The Two Dimensional Gierer-Meinhardt system with strong coupling
, 1999 We construct solutions with a single interior condensation point for the two-dimensional Gierer-Meinhardt system with strong coupling. The condensation point is located at a nondegenerate critical point of the diagonal part of the regular part
Winter, M +3 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Shifting Urban Freight Deliveries to the Off-Peak Hours: A Review of Theory and Practice
, 2017 This paper presents a comprehensive review of the literature on off-peak hour deliveries (OPHD). The review identifies different approaches and policy levers used in the past, such as the laissez-faire approach, a road pricing approach, an incentives ...
Brolinson, M\ue4rta +7 more
core +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
On a Two Dimensional Reaction-Diffusion System with Hypercyclical Structure
, 2000 We study a hypercyclical reaction-diffusion system which arises in the modeling of catalytic networks and describes the emerging of cluster states.
Winter, M, Wei, J
core
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Research on pulse electrodeposition of Fe-Ni alloy
AIP Advances, 2014 Fe-Ni alloys were fabricated on steel substrates by means of pulse electrodeposition in sulfate solutions. The layers were electrodeposited using different peak current densities, duty cycles and frequencies.
Yongsen Peng +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source