Results 81 to 90 of about 4,142,971 (284)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Multi-peak solutions for a planar Robin nonlinear elliptic problem with large exponent
Electronic Journal of Differential Equations, 2016 We consider the elliptic equation $\Delta u+u^p=0$ in a bounded smooth domain $\Omega$ in $\mathbb{R}^2$ subject to the Robin boundary condition $\frac{\partial u}{\partial\nu} +\lambda b(x)u=0$. Here $\nu$ denotes the unit outward normal vector on $\
Yibin Zhang, Lei Shi
doaj
Exp-Function Method for a Generalized MKdV Equation
Discrete Dynamics in Nature and Society, 2014 Under investigation in this paper is a generalized MKdV equation, which describes the propagation of shallow water in fluid mechanics. In this paper, we have derived the exact solutions for the generalized MKdV equation including the bright soliton, dark
Yuzhen Chai +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On a Two Dimensional Reaction-Diffusion System with Hypercyclical Structure [PDF]
, 2000 We study a hypercyclical reaction-diffusion system which arises in the modeling of catalytic networks and describes the emerging of cluster states.
Winter, M, Wei, J
core +3 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
International Journal of Electrochemical Science, 2010 Comparative studies of the electrochemical behaviour of Ag in aqueous NaCl, NaBr and NaI solutions of various concentrations ranging from 0.1 M to 1.0 M have been made by means of cyclic voltammetry and chronoamperometry techniques, complemented with SEM
Hamdy H. Hassan +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Uniqueness of positive periodic solutions with some peaks
Advances in Differential Equations, 2014 This work deals with the semi linear equation $-Δu+u-u^p=0$ in $\R^N$, $2\leq ...
Allain, Geneviève, Beaulieu, Anne
openaire +5 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source