Results 111 to 120 of about 495,930 (304)

Peak-locking centroid bias in Shack-Hartmann wavefront sensing

open access: yes, 2018
Shack-Hartmann wavefront sensing relies on accurate spot centre measurement. Several algorithms were developed with this aim, mostly focused on precision, i.e. minimizing random errors.
CM Correia (21891188)   +2 more
core  

Construction of single-peak solutions for Grushin equations via reduction method

open access: yesElectronic Journal of Differential Equations
In this article, we construct single-peak solutions for a class of Grushin equations by using the Lyapunov-Schmidt reduction method, whose concentration points locate on some special critical points of the potential function.
Yawei Wei, Xiaodong Zhou
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Multiple solutions for singularly perturbed semilinear elliptic equations in bounded domains

open access: yesAbstract and Applied Analysis, 2005
We are concerned with the multiplicity of solutions of the following singularly perturbed semilinear elliptic equations in bounded domains Ω:−ε2Δu+a(⋅)u=u|u|p−2 in Ω, u>0 in Ω, u=0 on ∂Ω.
Michinori Ishiwata
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Solutions with boundary layer and positive peak for an elliptic Dirichlet problem

open access: yes, 2009
In this paper, we study existence of solutions with boundary layer and peaks for an elliptic problem. We prove that the problem has a mountain-pass-type solution, which has a boundary layer and a single peak near the boundary. Moreover, we also study the
Li, Gongbao, Yang, Jianfu, Yan, Shusen
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Strongly interacting bumps for the schrodinger-newton equations

open access: yes, 2009
We study concentrated bound states of the Schrodinger-Newton equations Moroz, Penrose and Tod proved the existence and uniqueness of ground states.
Winter, M, Wei, J
core  

“Ghost Peak” Driven Structural Elucidation of a Photocatalytic Degradation Product from Brexpiprazole

open access: yes, 2019
Brexpiprazole which marketed as Rexulti® is a second-generation atypical antipsychotic. A seemingly random and uncontrollable “ghost peak” that vary from below the detection limit to ∼0.2% was observed occasionally during the development of HPLC method ...
Liang, Chen   +6 more
core   +1 more source

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