Results 91 to 100 of about 19,884 (196)

A Hybrid Machine Learning-Based Method for Classifying the Cushing's Syndrome With Comorbid Adrenocortical Lesions [PDF]

, 2011
Background: The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. It follows from a comprehensive statistical analysis that a number of antigens such as hTERT, PCNA and Ki-67
Deng, Youping, Huang, Xudong, Li, Jianling, Luo, Zuojie, Ma, Yan, Yang, Jack Y, Yang, Mary Qu   +6 more
core   +1 more source

Psychosocial burdens and unmet supportive care needs of partners and relatives of individuals with Li‐Fraumeni syndrome: A mixed‐methods study

Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Li‐Fraumeni syndrome (LFS) is a rare but highly penetrant cancer predisposition syndrome caused by pathogenic variants in the tumor suppressor gene TP53. Individuals diagnosed with LFS should adhere to intense surveillance programs for early tumor detection. The literature highlights several psychosocial challenges for this group. However, the
Senta Kiermeier, Sarah Schott, Juliane Nees, Christina M. Dutzmann, Farina Silchmüller, Christian P. Kratz, Myriam Keymling, Imad Maatouk   +7 more
wiley   +1 more source

Rare childhood tumors in a Turkish pediatric oncology center

Indian Journal of Medical and Paediatric Oncology, 2013
Background: It has been estimated that rare tumor rate is about 15% of all childhood cancer in United States. According to Turkish Pediatric Oncology Group (TPOG) datas, 8889 children were diagnosed between 2002 and 2008 in our country and 3.7% of them ...
Nurdan Tacyildiz, Derya Özyörük, Gülsan Yavuz, Emel Cabı Ünal, Handan Dinçaslan, Gülşah Oktay Tanyıldız, Zülfikar Gördü, Zeynep Şıklar, Merih Berberoğlu, Gönül Öcal   +9 more
doaj   +1 more source

Elevated Prolactin Levels Are Associated With Increased Severity and Psychiatric Symptoms in Anti‐N‐Methyl‐D‐Aspartate Receptor Encephalitis

Brain and Behavior, Volume 15, Issue 11, November 2025.
Association of serum PRL with anti‐NMDAR encephalitis. ABSTRACT Background Autoimmune encephalitis, predominantly anti‐N‐methyl‐D‐aspartate receptor (anti‐NMDAR) encephalitis, is a central nervous system (CNS) autoimmune disorder. Prolactin (PRL), a pro‐inflammatory hormone implicated in autoimmune pathogenesis, may play a role in anti‐NMDAR ...
Xiaoyu Ma, Yaxin Lu, Yingying Xu, Shougang Guo, Weiqi Wang, Wei Shang, Wei Qiu, Pin Wang, Yaqing Shu, Yuge Wang   +9 more
wiley   +1 more source

CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]

, 2018
Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core   +1 more source

Bilateral Adrenal Mass Secondary to Bilateral Infantile Neuroblastoma in an Infant With Beckwith‐Wiedemann Syndrome

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Infants with Beckwith‐Wiedemann syndrome face a high risk of embryonal tumors, necessitating early and consistent surveillance. This case illustrates how timely imaging and biochemical monitoring enabled successful non‐surgical management of bilateral adrenal neuroblastoma.
Mulualeme Nigusie, Gashaw Arega, Abel Hailu, Abreham Kassahun, Getasew Fikad, Tigest Chalachew, Bargude Balta   +6 more
wiley   +1 more source

TCF21/POD-1, a Transcritional Regulator of SF-1/NR5A1, as a Potential Prognosis Marker in Adult and Pediatric Adrenocortical Tumors

Frontiers in Endocrinology, 2018
With recent progress in understanding the pathogenesis of adrenocortical tumors (ACTs), identification of molecular markers to predict their prognosis has become possible.
Barbara dos Santos Passaia, Matheus Henrique Dias, Jean Lucas Kremer, Sonir Roberto Rauber Antonini, Madson Queiroz de Almeida, Maria Candida Barisson Villares Fragoso, Claudimara Ferini Pacicco Lotfi   +6 more
doaj   +1 more source

Hepatoblastoma and microRNA-483 two forms and one outcome [PDF]

, 2016
Hepatoblastoma (HB) is the most common liver cancer in infants younger than 3 years. Its onset has been associated with other genetic syndromes and some genetic and biochemical markers has been identified recently in this neoplasia.
Basso, E., Brunati, A., David, E., Flamini, Valentina, Magrelli, A., Romagnoli, R., Salvatore, M., Taruscio, D.   +7 more
core   +1 more source

Identification of a Novel TP53 Germline Mutation E285V in a Rare Case of Pediatric Adrenocortical Carcinoma and Choroid Plexus Carcinoma

Journal of Medical Genetics, 2008
Paediatric choroid plexus carcinomas (CPC) and adrenocortical carcinomas (ACC) are exceedingly rare tumours, each occurring at an annual rate of 0.3 cases per million children or less.
A. Russell-Swetek, A. West, J. Mintern, J. Jenkins, C. Rodríguez-Galindo, R. Ribeiro, G. Zambetti   +6 more
semanticscholar   +1 more source

Exceptional Clinical Response to Surgery in Somalian Child Affected by Hyper Secretive Adrenal Cortical Carcinoma

International Medical Case Reports Journal, 2022
Ahmed Adam Osman,1 Ahmed Omar Abdi,2 Ismail Mohamud Abdullahi,3 Mehmet Tahtabasi,4 Veysel Kaya5 1Department of Radiology, University of Health Sciences-Somalia Turkey Recep Tayyip Erdogan Education and Research Hospital, Mogadishu, Somalia; 2Department ...
Osman AA, Omar Abdi A, Mohamud Abdullahi I, Tahtabasi M, Kaya V   +4 more
doaj