Results 101 to 110 of about 19,884 (196)
Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma. [PDF]
Dysregulation of the seven-transmembrane (7TM) receptor Smoothened (SMO) and other components of the Hedgehog (Hh) signaling pathway contributes to the development of cancers including basal cell carcinoma (BCC) and medulloblastoma (MB).
Abagyan, Ruben +7 more
core +1 more source
EVALUATION OF CURRENT CLINICAL CRITERIA FOR LI-FRAUMENI SYNDROME IN A DIVERSE SAMPLE OF TP53 MUTATION CARRIERS [PDF]
Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome caused by heterozyogous germline mutations in the TP53 gene and characterized by an excess of early-onset cancers, high lifetime risk of cancer, and a wide range of tumor types ...
Parham, Emily A
core
Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study) [PDF]
Most prior studies of primary diagnosis in surgical pathology using whole slide imaging (WSI) versus microscopy have focused on specific organ systems or included relatively few cases.
Abels, Esther +33 more
core +1 more source
A patient with newly diagnosed breast cancer found to have mosaic TP53 likely pathogenic variant
CA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
Hetal D. Mistry +8 more
wiley +1 more source
Pediatric case of the day. Adrenocortical carcinoma. [PDF]
R A, Kaufman, R B, Towbin, W S, Ball
openaire +2 more sources
Histological differentiation between benign and malignant adrenocortical tumors is currently based on the criteria of Weiss et al. (Weiss criteria) and vimentin immunostaining, but the prognostic values of the criteria in pediatric cases are still unclear. We analyzed the histological features, immunostaining status of p53, vimentin, Ki67 and cyclin-A,
Yoko Misu +6 more
openaire +2 more sources
Background: Embryonal rhabdomyosarcoma (ERMS) of the urachus and adrenocortical carcinoma (ACC) are both rare conditions in children. We present the first case reported of synchronous urachal ERMS and ACC in a toddler with germline Casitas B-lineage ...
Mahek Desai +5 more
doaj +1 more source
Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
core
Epstein-Barr virus, infectious mononucleosis, and posttransplant lymphoproliferative disorders. [PDF]
PTLD may be considered as an "opportunistic cancer" in which the immunodeficiency state of the host plays a key role in fostering the environment necessary for abnormal lymphoproliferation.
Nalesnik, MA, Starzl, TE
core
Adrenocortical tumor in 20 months old female
Adrecortical virilizing tumors are rare in the pediatric age group. There is 1% incidence for adneral cancer. In comparison with adult patients , there is function adrenalectomy tumor in pediatric group.
Mohammad Reza Darabi Mahboob (MD) +1 more
doaj

