Results 81 to 90 of about 19,884 (196)

Frequency of cancer in children residing in Mexico City and treated in the hospitals of the Instituto Mexicano del Seguro Social (1996–2001) [PDF]

, 2004
Background The objective of this article is to present the frequency of cancer in Mexican children who were treated in the hospitals of the Instituto Mexicano del Seguro Social in Mexico City (IMSS-MC) in the period 1996–2001.
Servando Juárez-Ocaña, Guadalupe González-Miranda, Juan Manuel Mejía-Aranguré, Mario Enrique Rendón-Macías, María del Carmen Martínez-García, Arturo Fajardo-Gutiérrez, RW Miller, DM Parkin, JL Bernard, R Drup, AA Martín, RV Pérez-Perdomo, DL Sackett, SS Hayler, A Fajardo-Gutiérrez, A Fajardo-Gutiérrez, RJ Landis, A Fritz, E Kramárová, E Kramárová, M Massey-Stokes, A Fajardo-Gutiérrez, DE MacNeil, P Monge, M Linet, A Fajardo-Gutiérrez, L Parker, K Yamamoto, GR Buning   +28 more
core   +2 more sources

Pan‐cancer multi‐omics reveals DCAF7 as an immune‐modulating prognostic driver and Wnt/β‐catenin activator in hepatocellular carcinoma

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
DCAF7 is up‐regulated in various tumours and correlates with poor prognosis, particularly in LIHC. High DCAF7 expression is linked to CD4+ T cell infiltration, up‐regulation of immune checkpoint genes and increased tumour mutational burden, suggesting a role in tumour immune escape.
Ruina Luan, Hanbin Lin, Xin Zhao, Jianpeng Li, Maohe Chen, Shiping Luo, Xinjian Lin   +6 more
wiley   +1 more source

Virilizing adrenocortical carcinoma in a female child of Li-Fraumeni syndrome

Indian Journal of Pathology and Microbiology
Adrenocortical carcinoma is a rare malignancy and even rarer in infancy. Most of these tumors in the pediatric age group are hormonally active and predominantly present with virilization.
K V Vishnu Sankar, Debansu Sarkar, Dilip Kumar Pal, Uttara Chatterjee   +3 more
doaj   +1 more source

Germline TP53 mutational spectrum in French Canadians with breast cancer [PDF]

, 2012
Background Specific germline mutations in the hereditary breast-ovarian cancer susceptibility (HBC/HBOC) genes, BRCA1, BRCA2 and PALB2, have been shown to recur in French Canadians of Quebec, Canada, and this has been attributed to common
Suzanna L Arcand, Mohammed R Akbari, Anne-Marie Mes-Masson, Diane Provencher, William D Foulkes, Steven A Narod, Patricia N Tonin   +6 more
core   +1 more source

Clinical Features and Treatment Strategies of Li‐Fraumeni Syndrome Patients With Inherited TP53 Mutations

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
LFS with TP53 disease‐causing mutations may be potential beneficiaries of immune checkpoint inhibitors and targeted therapies. Therefore, NGS and PD‐L1 testing should be performed in all LFS patients. ABSTRACT Background Li‐Fraumeni syndrome is a rare autosomal dominant disorder caused by a pathogenic mutation of the tumor suppressor gene TP53.
Keyu Chen, Yufen Xu, Binbin Song, Yuyang Gu, Xiaofang Xu, Jun Cao, Meiyu Fang   +6 more
wiley   +1 more source

Adrenal tumors in children: Spectrum of presentation and surgical approach in a tertiary care institute

Indian Journal of Medical and Paediatric Oncology, 2020
Context: Adrenal tumors can arise either from cortex or from medulla; both the regions being structurally and functionally different. Current knowledge on childhood adrenocortical tumors (ACTs), the management approach, and the outcome is limited due to ...
Prasanta Kumar Tripathy, Kaumudee Pattnaik, Pradeep Kumar Jena, Hiranya Kishor Mohanty   +3 more
doaj   +1 more source

Evaluation of 9-cis retinoic acid and mitotane as antitumoral agents in an adrenocortical xenograft model [PDF]

, 2015
The available drug treatment options for adrenocortical carcinoma (ACC) are limited. In our previous studies, the in vitro activity of 9-cis retinoic acid (9-cisRA) on adrenocortical NCI-H295R cells was shown along with its antitumoral effects in a small
Baghy, Kornélia, Butz, Henriett, Hunyadi-Gulyás, Éva Csilla, Igaz, Péter, Kovalszky, Ilona, Medzihradszky F., Katalin, Micsik, Tamás, Nagy, Zoltán, Nyírő, Gábor, Patócs, Attila Balázs, Perge, Pál, Rácz, Gergely, Rácz, Károly   +12 more
core  

Repurposing Drugs in Oncology (ReDO)—mebendazole as an anti-cancer agent [PDF]

, 2014
Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types.
Bouche, Gauthier, Meheus, Lydie, Pantziarka, Pan, Sukhatme, Vidula, Sukhatme, Vikas P   +4 more
core   +1 more source

KDM3B Predicts Expression Signature, Prognosis Value, and Immune Characteristics of Cancers: A Pan‐Cancer Analysis

BioMed Research International, Volume 2026, Issue 1, 2026.
Dysregulation of histone modifications contributes to the development of cancer. The loss of methylation on histone H3 and H4 and the loss of acetylation serve as indicators of tumors. Histone demethylase KDM3B, which contains a JmjC domain, plays an important role in tumorigenesis and development by removing H3K9me1/2 methylation.
Liping Zhu, Xiaoyan Peng, Haile Yu, Xiaolu Fan, Zhoujie Ye, Baisakhi Banerjee   +5 more
wiley   +1 more source

MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen [PDF]

, 2016
Additional file 2: Figure S2. Representative flow cytometric histograms of CRC cell lines 72 h post transfection with pre-miR-210 and a control miRNA, respectively.
Anne Fassl, Jutta Richter, Katrin E. Tagscherer, Sabrina Schecher, Stephan Macher-Goeppinger, Tabea Sinkovic, Wilfried Roth   +6 more
core   +4 more sources