Results 61 to 70 of about 19,884 (196)

The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]

open access: yes, 2019
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia   +2 more
core   +1 more source

Adrenocortical tumors in children

open access: yesBrazilian Journal of Medical and Biological Research, 2000
Childhood adrenocortical tumors (ACT) are rare. In the USA, only about 25 new cases occur each year. In Southern Brazil, however, approximately 10 times that many cases are diagnosed each year.
R.C. Ribeiro   +7 more
doaj   +1 more source

Pediatric adrenal incidentaloma

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Adrenal incidentalomas are a rare finding in children. In adults, adrenal incidentalomas are often found during imaging or postmortem. When incidentally discovered in adults, the principles of management focus on estimating risk of malignancy, with ...
Joyce J.L.H. McRae   +2 more
doaj   +1 more source

Adrenocortical Tumors and Pheochromocytoma/Paraganglioma Initially Mistaken as Neuroblastoma—Experiences From the GPOH-MET Registry

open access: yesFrontiers in Endocrinology, 2022
In children and adolescents, neuroblastoma (NBL), pheochromocytoma (PCC), and adrenocortical tumors (ACT) can arise from the adrenal gland. It may be difficult to distinguish between these three entities including associated extra-adrenal tumors ...
Michaela Kuhlen   +13 more
doaj   +1 more source

Interventional oncology in children: Where are we now?

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel   +1 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick   +7 more
wiley   +1 more source

Adrenocortical carcinoma: Report of two cases

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Adrenocortical carcinoma (ACC) is a rare neoplasm with a slight predilection for female patients. We report two cases of ACC. The first case was of a 7-year-old girl who presented with clitoromegaly.
C Aparna   +3 more
doaj   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

O espectro das síndromes de hipertensão esteróide na infância e adolescência [PDF]

open access: yes, 2001
Arterial hypertension is not a privilege of adults. Besides renal and vascular causes, adrenocortical and correlated diseases must be considered when investigating a hypertensive child or adolescent.
Costa-Santos, Marivânia   +1 more
core   +3 more sources

Ectopic Low-grade Adrenocortical Carcinoma in the Spinal Region [PDF]

open access: yesAmerican Journal of Surgical Pathology, 2009
Ectopic adrenocortical neoplasms arising in the nervous system are very rare. We encountered an intradural, extramedullary case of an adrenocortical neoplasm of indeterminate malignant potential affecting a spinal nerve root in the distal lumbar region of a 5-month-old girl. The lesion recurred 6 months after the initial gross total resection.
Fausto J, Rodriguez   +4 more
openaire   +2 more sources

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