Results 51 to 60 of about 19,884 (196)

Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants [PDF]

, 2011
Adrenocortical carcinoma (ACC) is a rare, heterogeneous malignancy with a poor prognosis. According to WHO classification 2004, ACC variants include oncocytic ACCs, myxoid ACCs and ACCs with sarcomatous areas. Herein, we provide a comprehensive review of
Ronald R. de Krijger, Thomas G. Papathomas   +1 more
core   +1 more source

EDP-mitotane in children: reassuring evidence of reversible side-effects and neurotoxicity

Discover Oncology, 2022
Adrenocortical carcinoma affects one in 5 million children each year. Since prognosis for children older than 4 years is limited, clinicians often choose aggressive treatment with etoposide, doxorubicin, cisplatin (EDP) and mitotane after resection ...
Rebecca V. Steenaard, Marieke Rutjens, Madeleine H. T. Ettaieb, Max M. van Noesel, Harm R. Haak   +4 more
doaj   +1 more source

Adrenocortical carcinoma: A rare tumor in a 12-year-old girl

Indian Journal of Medical and Paediatric Oncology, 2018
A 12-year-old girl presented with intra-abdominal mass and cushingoid features. On investigation, she was diagnosed as a case of functioning adrenocortical carcinoma.
Sandesh V Parelkar, Dwarkanath V Kulkarni, Beejal V Sanghvi, Pooja Tiwari, Kedar P Mudkhedkar, Satej S Mhaskar, Rujuta Shah, Sonali S Mane, Kavimozhy Ilakkiya   +8 more
doaj   +1 more source

Venous Tumor Thrombosis and Pulmonary Metastases in a Case of Adrenal Neuroblastoma—Occurrence of Two Rare Manifestations in a Single Patient: Case Report and Review of Literature

Journal of Gastrointestinal and Abdominal Radiology, 2020
Unlike other pediatric extra cranial solid neoplasms, neuroblastomas have very low incidence of pulmonary metastases. Neuroblastomas also tend to encase rather than infiltrate the major vessels with very low incidence of tumor thrombus.
Somesh Singh, Seema Kembhavi, Sneha Shah, Tushar Vora, Girish Chinnaswamy, Sajid Qureshi   +5 more
doaj   +1 more source

Rare pediatric malignancies - A twenty year experience from an oncology institute in South India

Pediatric Hematology Oncology Journal, 2021
Background: Rare pediatric malignancies, as the name suggests, are not very frequently encountered in day to day practice. The European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) defines a rare childhood cancer as one that has an ...
Aarthi Viswanathan, Arun Kumar, Avinash Thumallapalli, Prakruthi S. Kaushik, B.S. Aruna kumari, L. Appaji, Nuthan Kumar   +6 more
doaj   +1 more source

Low-dose mitotane-induced neurological and endocrinological complication in a 5-year-old girl with adrenocortical carcinoma [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Mitotane is an adrenolytic drug that exhibits therapeutic effects within a narrow target range (14–20 μg/dL). Various complications develop if the upper limit is exceeded.
You Joung Heo, Jae Ho Yoo, Yun Soo Choe, Sang Hee Park, Seung Bok Lee, Hyun A Kim, Jung Yoon Choi, Young Ah Lee, Byung Chan Lim, Hee Won Chueh   +9 more
doaj   +1 more source

Role of the mTOR pathway in normal and tumoral adrenal cells [PDF]

, 2010
The mammalian target of rapamycin (mTOR) is a kinase of the phosphoinositide 3-kinase (PI3Ks)/protein kinase B (PKB or AKT) signaling pathway, which is one of the most important intracellular mediators of the activity of growth factors receptors ...
Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Martino, M.C. (Maria Cristina) de, Pivonello, R. (Rosario)   +3 more
core   +1 more source

Association of the germline R337H mutation with breast cancer in southern Brazil [PDF]

, 2008
Background The germline TP53-R337H mutation is strongly associated with pediatric adrenocortical tumors (ACT) in southern Brazil; it has low penetrance and limited tissue specificity in most families and therefore is not associated with Li-Fraumeni ...
Srivastava Kumar, Ganti Ramapriya, Zambetti Gerard P, Ribeiro Raul C, Mastellaro Maria, Seidinger Ana, Assumpção Juliana G, Shurtleff Sheila, Pei Deqing, Zeferino Luiz, Dufloth Rozany M, Brandalise Silvia, Yunes José   +12 more
core   +2 more sources

Japanese Clinical Practice Guidelines for Vascular Tumors, Vascular Malformations, Lymphatic Malformations, and Lymphangiomatosis 2022

The Journal of Dermatology, Volume 53, Issue 5, Page e257-e356, May 2026.
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita, Kosuke Ishikawa, Sadanori Akita, Katsuyoshi Koh, Satoru Sasaki, Masatoshi Jinnin, Hidefumi Mimura, Keigo Osuga, Michio Ozeki, Michiko Nagahama, Akihiro Fujino, Yoko Aoki, Akiko Asai, Noriko Aramaki‐Hattori, Ryohei Ishiura, Masanori Inoue, Yuki Iwashina, Takafumi Ohshiro, Keiko Ogawa, Mine Ozaki, Junko Ochi, Shiro Onozawa, Motoi Kato, Takahide Kaneko, Tamihiro Kawakami, Akira Kitagawa, Masakazu Kurita, Yoshihiro Kuwano, Taro Kono, Shien Seike, Shinsuke Takagi, Nobuyuki Takakura, Takao Tachibana, Shuichi Tanoue, Kumiko Chuman, Hiroki Nakaoka, Yasuhiro Nakamura, Fumio Nagai, Yasunari Niimi, Shunsuke Nosaka, Taiki Nozaki, Tadashi Nomura, Kazuki Hashimoto, Ayato Hayashi, Satoshi Hirakawa, Takeshi Hirabayashi, Taizo Furukawa, Hiroshi Furukawa, Yumiko Hori, Takanobu Maekawa, Kentaro Matsuoka, Hideki Mori, Eiichi Morii, Akira Morimoto, Yuta Moriwaki, Shunsuke Yuzuriha, Naoaki Rikihisa, Munezumi Fujita, Yasuyuki Yamahana, Kyoichi Deie, Asami Tozawa, Daisuke Hasegawa, Akira Higashiyama, Daisuke Maeda, Sachiko Asayama, Yuhki Arai, Yohei Iwata, Mayu Uka, Hidehito Usui, Mizuki Uchiyama, Saori Endo, Hideki Endo, Rintaro Ono, Naoya Oshima, Toshihiro Otsuka, Kuniaki Ohara, Shinji Kagami, Tomo Kakihara, Mototoshi Kato, Hiroki Kanamori, Masafumi Kamata, Ami Kawaguchi, Akiko Kishi, Hiroshi Kitagawa, Kiyokazu Kim, Tamotsu Kobayashi, Takeshi Saito, Yusuke Shikano, Shuichi Shimada, Keisuke Suzuki, Masataka Takahashi, Shohei Takami, Reiko Takeda, Aya Tanaka, Kaishu Tanaka, Satoru Tamura, Masashi Tamura, Kanako Danno, Kenji Tsuboi, Yuta Nakajima, Ryo Nakatani, Miho Noguchi, Akifumi Nozawa, Naoki Hashizume, Masashi Hayakawa, Daichi Hayashi, Takaya Fukumoto, Mamoru Honda, Norifumi Matsuda, Hayato Maruguchi, Naoki Murakami, Kiichiro Yaguchi, Shiho Yasue, Hiroki Yoshihara, Rika Yoshimatsu, Kiyohito Yamamoto, Shinji Wada   +116 more
wiley   +2 more sources

New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells

Clinics
OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França, Antonio M. Lerario, Maria Candida B.V. Fragoso, Claudimara Ferini Pacicco Lotfi   +3 more
doaj   +1 more source