Results 31 to 40 of about 1,054,709 (177)

Embolization in an adrenocortical carcinoma as palliative therapy [PDF]

, 1999
Background: With an annual incidence of 0.2% of new cases per 100,000 inhabitants, adrenocortical carcinoma is rare. In advanced tumor only palliative treatment modalities are practicable. Because of scarcity of the tumor, standard treatment has not been
Kühl, M., Forstpointner, Roswitha, Braunschweig, R., Schalhorn, Andreas, Lang, N., Meissner, H., H. Meißner, M. Kühl, N. Lang, A. Schalhorn, R. Forstpointner, R. Braunschweig   +11 more
core   +1 more source

Long-term survival outcomes of pediatric adrenal malignancies: An analysis with the upstaged SEER registry during 2000-2019

Frontiers in Endocrinology, 2022
ObjectiveTo investigate the clinicopathological characteristics and long-term survival outcomes of pediatric adrenal malignancies.MethodThis study retrospectively analyzed children with pathologically confirmed pediatric adrenal malignancies from ...
Zemin Lv, Yunyun Yu, Yangmei Luo, Song Lin, Xuang Xiang, Xiaowen Mao, Shigang Cheng   +6 more
doaj   +1 more source

Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]

, 2013
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Lucile Lefèvre, Ragazzon, Bruno, Constanze Hantel (280561), Guillaud-Bataille, Marine, Bruno Ragazzon (140444), Launay, Pierre, Stéphane Bonnet (280565), Marthe Rizk-Rabin (280575), Marine Guillaud-Bataille (9131), Karine Perlemoine, Lefèvre, Lucile, Sébastien Gaujoux (280559), Tissier, Frédérique, Hantel, Constanze, Frédérique Tissier (140448), Lucile Lefèvre (280570), Rizk-Rabin, Marthe, Karine Perlemoine (280567), Bertherat, Jérôme, Stéphane Bonnet, Bonnet, Stéphane, Sébastien Gaujoux, Perlemoine, Karine, Jérôme Bertherat, Bruno Ragazzon, Beuschlein, Felix, Marthe Rizk-Rabin, Frédérique Tissier, Pierre Launay (280563), Jérôme Bertherat (140471), Felix Beuschlein, Marine Guillaud-Bataille, Constanze Hantel, Felix Beuschlein (158361), Gaujoux, Sébastien, Pierre Launay   +35 more
core   +1 more source

Retroperitoneoscopic adrenalectomy in an infant with adrenocortical virilizing tumor

São Paulo Medical Journal, 2002
CONTEXT: Adrenocortical virilizing tumors are rare in the pediatric age group. Laparoscopic surgery is the gold standard method for treatment of adrenal functional tumors under 6 cm in size, in adults.
Marcos Tobias-Machado, Jairo Cartum, Telma Murias Santos-Machado, Heloísa Amaral Gaspar, Alexandre Sibanto Simões, Ricardo Cruz, Renata Rodrigues, Roberto Vaz Juliano, Eric Roger Wroclawski   +8 more
doaj   +1 more source

Li-Fraumeni syndrome: Adrenal cortical tumor in a newborn followed by a choroid plexus tumor

Journal of Pediatric Surgery Case Reports, 2018
Adrenocortical tumors (ACTs) are rare in children, comprising
Jamie E. Anderson, Rebecca A. Stark
doaj   +1 more source

Adrenocortical tumors in children: Sri Lankan experience from a single center, and a mini review

Journal of Medical Case Reports, 2023
Background Pediatric adrenocortical tumors include both benign adenomas and highly virulent malignant tumors. However, they are very rare among children.
Naotunna Palliya Guruge Chamidri Randika Naotunna, Harankaha Vidanalage Dinendra Nishadini Siriwardana, Balagamage Chamila Lakmini, Dilhara Senani Gamage, Sandani Gunarathna, Malik Samarasinghe, Sanjeewa Gunasekara, Navoda Atapattu   +7 more
doaj   +1 more source

EDP-mitotane in children: reassuring evidence of reversible side-effects and neurotoxicity

Discover Oncology, 2022
Adrenocortical carcinoma affects one in 5 million children each year. Since prognosis for children older than 4 years is limited, clinicians often choose aggressive treatment with etoposide, doxorubicin, cisplatin (EDP) and mitotane after resection ...
Rebecca V. Steenaard, Marieke Rutjens, Madeleine H. T. Ettaieb, Max M. van Noesel, Harm R. Haak   +4 more
doaj   +1 more source

Adrenocortical carcinoma: A rare tumor in a 12-year-old girl

Indian Journal of Medical and Paediatric Oncology, 2018
A 12-year-old girl presented with intra-abdominal mass and cushingoid features. On investigation, she was diagnosed as a case of functioning adrenocortical carcinoma.
Sandesh V Parelkar, Dwarkanath V Kulkarni, Beejal V Sanghvi, Pooja Tiwari, Kedar P Mudkhedkar, Satej S Mhaskar, Rujuta Shah, Sonali S Mane, Kavimozhy Ilakkiya   +8 more
doaj   +1 more source

Venous Tumor Thrombosis and Pulmonary Metastases in a Case of Adrenal Neuroblastoma—Occurrence of Two Rare Manifestations in a Single Patient: Case Report and Review of Literature

Journal of Gastrointestinal and Abdominal Radiology, 2020
Unlike other pediatric extra cranial solid neoplasms, neuroblastomas have very low incidence of pulmonary metastases. Neuroblastomas also tend to encase rather than infiltrate the major vessels with very low incidence of tumor thrombus.
Somesh Singh, Seema Kembhavi, Sneha Shah, Tushar Vora, Girish Chinnaswamy, Sajid Qureshi   +5 more
doaj   +1 more source

Effects of o,p’-DDE, a Mitotane Metabolite, in an Adrenocortical Carcinoma Cell Line

Pharmaceuticals, 2022
In South Brazil, the incidence of pediatric adrenocortical carcinoma (ACC) is higher than in other regions and countries worldwide. The ACC treatment includes therapy with mitotane, the only adrenolytic drug approved by the FDA.
Camila Bach, Claudia Rita Corso, Alan de Almeida Veiga, Mariana Martins Paraizo, Lauro Mera de Souza   +4 more
doaj   +1 more source