Adrenocortical carcinoma: Pediatric aspects (Review)
Adrenocortical carcinoma (adrenal cortex-derived cancer), an orphan malignancy, is a very aggressive disease that affects both adults and children with an annual incidence of 1-2 adult and 0.2-0.38 pediatric cases/million (in the pediatric population it represents 0.2% of all cancers), with a female predominance.
Florica, Sandru +5 more
openaire +3 more sources
DAX-1 Expression in Pediatric Rhabdomyosarcomas: Another Immunohistochemical Marker Useful in the Diagnosis of Translocation Positive Alveolar Rhabdomyosarcoma [PDF]
OBJECTIVES: The aim of this study was to investigate the expression of DAX-1 in a series of pediatric rhabdomyosarcomas (RMS) with known translocation and compare it to Ap2\u3b2, known to be selectively expressed in ARMS. DESIGN: We revised a series of
Alaggio, Rita +10 more
core +20 more sources
Mature Cystic Teratoma of the Right Adrenal Gland in a Pediatric Patient: A Case Report. [PDF]
ABSTRACT Adrenal teratomas are rare neoplasms, most often benign but with potential for malignant transformation, particularly in the pediatric population. A seven‐year‐old girl from kawasoti, Nepal, presented with intermittent right‐sided abdominal pain for 2 months, initially attributed to dietary factors such as junk food intake.
Gautam A +4 more
europepmc +2 more sources
Pediatric Adrenocortical Carcinoma Presenting With Virilization: A Case of a Low-Grade Tumor in a Young Child. [PDF]
Askar A +2 more
europepmc +2 more sources
Adrenocortical carcinoma in a pediatric patient with li-fraumeni-like Syndrome: an endemic condition in southern Brazil [PDF]
A 12-year-old boy with germline TP53-R337H mutation and family history of early adrenocortical carcinoma (ACC) was admitted to hospital with abdominal pain and distention. During the physical examination he presented cushingoid facies, high blood pressure and pulse rate.
Mendes Knabben, Mariana +4 more
openaire +4 more sources
Aspectos clínicos e moleculares de tumor adrenocortical metacrônico pediátrico [PDF]
The occurrence of metachronous adrenocortical carcinoma has rarely been described. We report a case of a child with virilizing adrenocortical metachronous tumors that, despite several metastases, presented long-term survival (15 years).
ALENCAR, Guilherme Asmar +8 more
core +2 more sources
Pediatric adrenocortical carcinoma revealed by isolated Cushing syndrome: A case report
Background: Adrenocortical carcinoma accounts for less than 0.2% of all pediatric malignancies. Virilization is the most common revealing sign, whereas hyperaldosteronism and Cushing syndrome are less common.We report a case of adrenocortical carcinoma which was revealed by Cushing syndrome and successfully treated in an adolescent girl.
Hakima Chafaaoui +4 more
openaire +2 more sources
GLUT1 expression in pediatric adrenocortical tumors: a promising candidate to predict clinical behavior [PDF]
Background: Discrimination between benign and malignant tumors is a challenging process in pediatric adrenocortical tumors. New insights in the metabolic profile of pediatric adrenocortical tumors may contribute to this distinction, predict prognosis, as
Allolio +60 more
core +2 more sources
New directions for the treatment of adrenal insufficiency [PDF]
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen +69 more
core +2 more sources
Bilateral Adrenal Mass Secondary to Bilateral Infantile Neuroblastoma in an Infant With Beckwith-Wiedemann Syndrome. [PDF]
ABSTRACT Infants with Beckwith‐Wiedemann syndrome face a high risk of embryonal tumors, necessitating early and consistent surveillance. This case illustrates how timely imaging and biochemical monitoring enabled successful non‐surgical management of bilateral adrenal neuroblastoma.
Nigusie M +6 more
europepmc +2 more sources

