Results 61 to 70 of about 6,153 (148)
Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma. [PDF]
, 2019 Dysregulation of the seven-transmembrane (7TM) receptor Smoothened (SMO) and other components of the Hedgehog (Hh) signaling pathway contributes to the development of cancers including basal cell carcinoma (BCC) and medulloblastoma (MB).
Abagyan, Ruben +7 more
core +1 more source
Birth characteristics and childhood carcinomas [PDF]
, 2011 BACKGROUND: Carcinomas in children are rare and have not been well studied. METHODS: We conducted a population-based case–control study and examined associations between birth characteristics and childhood carcinomas diagnosed from 28 days to 14 years ...
Carozza, Susan E +10 more
core +2 more sources
, 2023 <div>Abstract<p><b>Purpose:</b> Pediatric adrenocortical carcinoma (ACC) is a rare and highly aggressive malignancy. Conventional chemotherapeutic agents have shown limited utility and are largely ineffective in treating children with advanced ACC.
Gerard P. Zambetti +9 more
openaire +1 more source
New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells [PDF]
, 2017 OBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Fragoso, Maria Candida B.V. +3 more
core +3 more sources
Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases (Pivotal Study) [PDF]
, 2018 Most prior studies of primary diagnosis in surgical pathology using whole slide imaging (WSI) versus microscopy have focused on specific organ systems or included relatively few cases.
Abels, Esther +33 more
core +1 more source
, 1983 Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
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CPEM: Accurate cancer type classification based on somatic alterations using an ensemble of a random forest and a deep neural network [PDF]
, 2019 With recent advances in DNA sequencing technologies, fast acquisition of large-scale genomic data has become commonplace. For cancer studies, in particular, there is an increasing need for the classification of cancer type based on somatic alterations ...
Jeong, Hyoung-oh +3 more
core +1 more source
Pediatric case of the day. Adrenocortical carcinoma. [PDF]
RadioGraphics, 1987 R A, Kaufman, R B, Towbin, W S, Ball
openaire +2 more sources
CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]
, 2018 Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core +1 more source